内蒙古汉族人群中糖尿病血液透析患者与糖尿病腹膜透析患者心血管疾病危险因素比较  

Risk factors for cardiovascular disease in hemodialysis vs peritoneal dialysis patients with diabetes in Han population of Inner Mongolia

作　　者：南蕾[1] 米焱[1] 贾妮亚[1] 李增艳[1] 张艳辉[1] 王彩丽[1] Nan Lei;Mi Yan;Jia Niya;Li Zengyan;Zhang Yanjun;Wang Caili(Department of Nephrology,The First Affiliated Hospital of Baotou Medical College,Baotou 014010,China)

机构地区：[1]包头医学院第一附属医院肾内科,014010

出　　处：《国际移植与血液净化杂志》2021年第5期27-31,共5页International Journal of Transplantation and Hemopurification

摘　　要：目的比较内蒙古汉族人群中糖尿病血液透析患者和糖尿病腹膜透析患者心血管疾病的危险因素。方法回顾性分析本院2000年1月至2018年6月收治的维持性透析治疗>3个月的糖尿病患者,均为内蒙古汉族人,应用倾向性评分法匹配出两组患者。空腹抽血,测定血糖、糖化血红蛋白、甘油三酯、低密度脂蛋白、高密度脂蛋白、C反应蛋白水平。利用多普勒超声评估颈动脉斑块情况。结果血液透析患者和腹膜透析患者的平均年龄、性别、体质指数及透析持续时间差异无统计学意义(P>0.05)。糖尿病腹膜透析患者血糖、低密度脂蛋白和甘油三酯水平明显高于血液透析患者(P<0.05)。Kaplan-Meier生存分析显示,血液透析患者1年生存率高于腹膜透析患者(P<0.05)。结论在本研究纳入的内蒙古汉族人群中,糖尿病腹膜透析患者心血管危险因素较血液透析患者更为常见。Objective To compared the cardiovascular risk factors for hemodialysis vs peritoneal dialysis patients with diabetes in Han population of Inner Mongolia.Methods A retrospective analysis was conducted in Han diabetic patients who maintained dialysis for more than 3 months from January 2000 to June 2018 in our hospital.Venous blood samples were taken,and the levels of serum glucose,triglyceride,low-density lipoprotein(LDL),high-density lipoprotein(HDL),and C-reactive protein were measured.The presence of atherosclerotic plaques in the carotid artery was evaluated by carotid doppler ultrasound.Results No statistical significance was found in mean age,gender,body mass index or dialysis duration between the hemodialysis patients and peritoneal dialysis patients(P>0.05).The levels of serum glucose,LDL and triglyceride were significantly higher in peritoneal dialysis patients when compared to hemodialysis patients(P<0.05).Conclusions In our study,cardiovascular risk factors were more common in diabetic patients undergoing peritoneal dialysis.

关 键 词：心血管危险因素 动脉粥样硬化 血液透析 腹膜透析 糖尿病 

分 类 号：R587.2[医药卫生—内分泌] R692[医药卫生—内科学] R54[医药卫生—临床医学]