丙泊酚与右美托咪定分别复合瑞芬太尼对小儿麻醉维持喉罩通气中通气状态及应激反应的影响  

Effects of propofol or dexmedetomidine combined with remifentanil on ventilation status and stress response during laryngeal mask ventilation in children under anesthesia maintenance

作　　者：李小艳 康俊 LI Xiaoyan;KANG Jun(Anesthesiology Department,the People's Hospital of Yuyang District,Yulin 719000,China)

机构地区：[1]榆林市榆阳区人民医院麻醉科,陕西榆林719000

出　　处：《临床医学研究与实践》2021年第34期118-120,共3页Clinical Research and Practice

摘　　要：目的探讨丙泊酚与右美托咪定分别复合瑞芬太尼对小儿麻醉维持喉罩通气中通气状态及应激反应的影响。方法选取2019年10月至2020年10月收治的100例手术患儿,按照随机数字表法将其分为A组和B组,各50例。A组采用丙泊酚复合瑞芬太尼进行麻醉,B组采用右美托咪定复合瑞芬太尼进行麻醉。比较两组的麻醉效果。结果T_(1)、T_(2)、T_(3)、T_(4)、T5时,A组的SpO_(2)均高于B组(P<0.05)。T_(2)、T_(3)、T_(4)、T5时,A组的心率、平均动脉压均低于B组(P<0.05)。A组的不良反应总发生率为4.00%,显著低于B组的20.00%(P<0.05)。结论丙泊酚复合瑞芬太尼较右美托咪定复合瑞芬太尼的麻醉效果更好,丙泊酚复合瑞芬太尼能进一步改善小儿麻醉维持喉罩通气中的通气状态,减轻应激反应,也能降低不良反应发生率。Objective To investigate the effects of propofol or dexmedetomidine combined with remifentanil on ventilation status and stress response during laryngeal mask ventilation in children under anesthesia maintenance.Methods A total of 100 surgical children treated from October 2019 to October 2020 were selected and divided into group A and group B according to random number table method,with 50 cases in each group.The group A was anesthetized with propofol combined with remifentanil,and the group B was anesthetized with dexmedetomidine combined with remifentanil.The anesthetic effects of the two groups were compared.Results At T_(1),T_(2),T_(3),T_(4) and T5,the SpO_(2) in the group A were higher than that in the group B(P<0.05).At T_(2),T_(3),T_(4) and T5,the heart rate and mean arterial pressure in the group A were lower than those in the group B(P<0.05).The total incidence of adverse reactions in the group A was 4.00%,which was significantly lower than 20.00% in the group B(P<0.05).Conclusion Propofol combined with remifentanil has better anesthetic effect than dexmedetomidine combined with remifentanil.Propofol combined with remifentanil can further improve ventilation status during laryngeal mask ventilation in children under anesthesia maintenance,reduce stress response,and decrease the incidence of adverse reactions.

关 键 词：丙泊酚 右美托咪定 瑞芬太尼 麻醉维持 喉罩通气 通气状态 应激反应 

分 类 号：R614[医药卫生—麻醉学]