艾滋病合并肛周脓肿患者预后的影响因素  

Influencing factors of prognosis of patients with AIDS combined with perianal abscess

作　　者：郑璐 陈绛青[1] 欧阳水明 张全辉[2] 黄义华[3] 邬小萍[4] ZHENG Lu;CHEN Jiang-qing;OUYANG Shui-ming;ZHANG Quan-hui;HUANG Yi-hua;WU Xiao-ping(Department of Infection,Nanchang Ninth Hospital,Jiangxi Province,Nanchang,330029,China;Department of Anorectal,Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine,Jiangxi Province,Nanchang,330006,China;Department of Surgery,Nanchang Ninth Hospital,Jiangxi Province,Nanchang,330029,China;Department of Infection,the First Affiliated Hospital of Nanchang University,Jiangxi Province,Nanchang,330006,China)

机构地区：[1]南昌市第九医院感染科,江西南昌330029 [2]江西中医药大学附属医院肛肠科,江西南昌330006 [3]南昌市第九医院外科,江西南昌330029 [4]南昌大学第一附属医院感染科,江西南昌330006

出　　处：《中国当代医药》2021年第33期64-67,79,共5页China Modern Medicine

基　　金：江西省卫生健康委科技计划(20204120)。

摘　　要：目的探讨艾滋病合并肛周脓肿患者预后的影响因素。方法选取2019年5月至2020年12月南昌市第九医院收治的60例艾滋病合并肛周脓肿患者作为观察组,选取同期江西中医药大学附属医院收治的60例无艾滋病的单纯肛周脓肿患者作为对照组。比较两组预后情况,并分析艾滋病合并肛周脓肿患者预后的影响因素。结果观察组预后不良发生率高于对照组,差异有统计学意义(P<0.05);经logistic回归分析检验显示,年龄大、CD4+细胞计数<150个/μL、未接受抗病毒治疗、白细胞计数(WBC)水平高、白介素-6(IL-6)水平高、白介素-10(IL-10)水平高是艾滋病合并肛周脓肿患者预后不良的影响因素(OR>1,P<0.05)。结论艾滋病合并肛周脓肿患者预后不良发生率较高,年龄大、CD4+细胞计数<150个/μL、未接受抗病毒治疗、WBC水平高、IL-6水平高、IL-10水平高是艾滋病合并肛周脓肿患者预后不良的影响因素,临床应关注上述影响因素,积极给予对应干预措施,以改善预后。Objective To explore the Influencing factors of prognosis of patients with acquired immune deficiency syndrome combined with perianal abscess.Methods A total of 60 patients with acquired immune deficiency syndrome complicated with perianal abscess admitted to the Ninth Hospital of Nanchang from May 2019 to December 2020 were selected as the observation group,and 60 patients with a simple perianal abscess without acquired immune deficiency syndrome admitted to Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine at the same period were selected as the control group.The prognosis of the two groups was compared,and the influencing factors of the prognosis of acquired immune deficiency syndrome patients with perianal abscess were analyzed.Results The incidence of poor prognosis in the observation group was higher than that in the control group,the difference was statistically significant(P<0.05).Logistic regression analysis showed that older age,the number of CD4+cells<150 cells/μL,no acceptance antiviral treatment,high level of white blood cell count(WBC),high level of interleukin-6(IL-6)and high level of interleukin-10(IL-10)were the influencing factors of poor prognosis in acquired immune deficiency syndrome patients with perianal abscess(OR>1,P<0.05).Conclusion Acquired immune deficiency syndrome patients with perianal abscess have a higher incidence of poor prognosis,older age,and number of CD4+cells<150 cells/μL no perianal abscess,high WBC level,high IL-6 level and high IL-10 level are acquired immune deficiency syndrome Influencing factors for the poor prognosis of patients with perianal abscess.The clinical should pay attention to the above factors and actively give corresponding intervention measures to improve the prognosis.

关 键 词：艾滋病 肛周脓肿 预后 危险因素 

分 类 号：R512.91[医药卫生—内科学]