藏药白脉软膏实效性临床研究  

Clinical Study on the Effectiveness of Tibetan Baimai Ointment

作　　者：王荣田 陈兆军 吴俊德 何海军[2] 王均玉[2] 史栋梁[3] 吕刚[4] 李丽 朱蜀云[6] 胡正学 陈卫衡 WANG Rongtian;CHEN Zhaojun;WU Junde;HE Haijun;WANG Junyu;SHI Dongliang;LYU Gang;LI Li;ZHU Shuyun;HU Zhengxue;CHEN Weiheng(Beijing University of Chinese Medicine Third Affiliated Hospital,Beijing 100029,China;Wangjing Hospital of CACMS,Beijing 100102,China;Henan Province Hospital of TCM,Zhengzhou 450002,China;Chengdu First People’s Hospital,Chengdu 610021,China;Central Hospital of China Railway 17th Bureau Group,Taiyuan 030032,China;Beijing Gulou Hospital of TCM,Beijing 100009,China;Dunhuang Tibetan Medicine Hospital,Tianzhu 733200,Gansu China)

机构地区：[1]北京中医药大学第三附属医院,北京100029 [2]中国中医科学院望京医院 [3]河南省中医院 [4]成都市中西医结合医院(成都市第一人民医院) [5]中铁十七局集团中心医院 [6]北京市鼓楼中医医院 [7]天祝藏族自治县藏医药开发研究所(敦煌市藏医专科医院)

出　　处：《中国中医骨伤科杂志》2021年第11期32-37,共6页Chinese Journal of Traditional Medical Traumatology & Orthopedics

摘　　要：目的:探讨藏药白脉软膏治疗骨骼肌肉系统疾病的疗效及安全性。方法:采用实效性自身前后对照临床设计,纳入多家医院2019年7月至2020年7月,采用白脉软膏治疗的颈椎病,肩颈肌筋膜炎、腰背肌筋膜炎,肩周炎,屈指肌腱狭窄性腱鞘炎,桡骨茎突狭窄性腱鞘炎,下腰痛患者1360例。3次/d,1周1个疗程,共2个疗程,每周随访1次,并记录每位患者的真实干预治疗措施,以NRS评分、压痛程度、功能障碍评分及局部功能障碍评价。采用科研云线上平台进行数据收集和管理。结果:应用白脉软膏治疗1周,疼痛、压痛、活动受限、功能障碍等评分均得到明显改善,差异有统计学意义(P<0.01);NRS指数有效率为81.97%,显效率为13.80%;压痛程度有效率为70.00%,显效率为17.75%;功能障碍有效率为73.24%,显效率为29.44%。用药2周,较治疗1周的改善程度更加显著,差异有统计学意义(P<0.01);NRS指数有效率为97.04%,显效率为70.28%;压痛程度有效率为89.01%,显效率为62.39%;功能障碍有效率为89.72%,显效率为77.61%。FAS集与PPS集分析结果相当。结论:白脉软膏在临床上应用于腱鞘炎、肌筋膜炎、颈椎病、肩周炎、下腰痛等各种骨骼肌肉系统疾病的治疗,具有解痉止痛,缓解肌紧张,改善患者运动功能障碍等功效,其疗效确切,安全性好,持续用药可增加临床获益。Objective:To investigate the efficacy and safety of Baimai ointment on the treatment of musculoskeletal diseases and to provide evidence for clinical application.Methods:1360 patients with cervical spondylosis,scapulocervical myofascitis,lumbodorsal myofascitis,scapulohumeral periarthritis,stenosing tenosynovitis of flexor digitorum,stenosing tenosynovitis of radial styloid process and low back pain treated with Baimai ointment were enrolled from July 2019 to July 2020.The using of dosage was three times a day,one course a week,two courses in total.The patients were followed up once a week.The real intervention measures of each patient were recorded and evaluated by NRS score,tenderness degree,dysfunction score and local dysfunction.The research cloud online platform was used for data collection and management.Results:After one week treatment with Baimai ointment,the score of pain,tenderness,activity limitation,dysfunction and other symptoms were significantly improved(P<0.01).The effective rate of NRS index was 81.97%,and the significantly effective rate was 13.80%;the effective rate of tenderness degree was 70.00%,and the significantly effective rate was 17.75%;the effective rate of functional disorder was 73.24%,and the significantly effective rate was 29.44%.After two weeks of continuous treatment,the improvement degree was more significant than that after one week of treatment(P<0.01).The effective rate of NRS index was 97.04%,and the significantly effective rate was 70.28%;the effective rate of tenderness degree was 89.01%,and the significantly effective rate was 62.39%;the effective rate of dysfunction was 89.72%,and the significantly effective rate was 77.61%.The results of FAS set and PPS set were similar.Conclusion:Baimai ointment has the efficacies of spasmolysis,pain relief,muscle tension relief and motor dysfunction improvement on the treatment of tenosynovitis,myofascitis,cervical spondylosis,scapulohumeral periarthritis,low back pain and other skeletal muscle system diseases in clinical.Its curativ

关 键 词：藏药 白脉软膏 腱鞘炎 肌筋膜炎 肩周炎 颈椎病 下腰痛 

分 类 号：R274.39[医药卫生—中医骨伤科学]