维持性血液透析患者肌少症患病率的meta分析  

Prevalence of sarcopenia in maintenance hemodialysis patients:a meta-analysis

作　　者：李兰 温贤秀[2] 夏琪[3] 李艳[4] 肖力 谢林娟 LI Lan;WEN Xian-xiu;XIA Qi;LI Yan;XIAO Li;XIE Lin-juan(School of Nursing,Chengdu University of Traditional Chinese Medicine,Chengdu,Sichuan 610075,China;不详)

机构地区：[1]成都中医药大学护理学院,四川成都610075 [2]四川省人民医院护理部,四川成都610072 [3]四川省人民医院PICC中心 [4]四川省人民医院血液透析中心

出　　处：《现代预防医学》2021年第22期4214-4218,共5页Modern Preventive Medicine

基　　金：四川省卫生健康委课题(19PJ123);四川省科技计划项目软件科学研究课题(2020JDR0284)。

摘　　要：目的系统评价维持性血液透析患者骨骼肌减少症(肌少症)的患病率情况。方法全面检索中英文数据库:中国知网(CNKI)、中国生物医学文献数据库(CBM)、万方数据库(Wanfang Date)、维普数据库(VIP),英文数据库Pubmed、Embase、web of science、EBSCO查找有关维持性血液透析患者肌少症患病情况的相关研究。对纳入的文献按照纳排标准进行筛选、提取所需数据并按照标准严格进行文献质量评价后,通过Stata 12.0软件进行meta分析。结果本研究最终纳入了15篇文献,共计2 561例维持性血液透析患者,文献质量评价均为中高等质量文献。Meta分析结果显示,维持性血液透析患者肌少症总患病率为31.2%(95%CI:24.9%~37.6%),亚洲患者患病率为31.8%(95%CI:24.0%~39.6%)。男性肌少症患病率较女性患者高(37.0%vs 28.0%),使用AWGS诊断标准肌少症患病率高于EWGSOP诊断标准(36.8%vs 26.2%),使用DEXA肌量评估方法肌少症患病率稍低于BIA肌量评估方法(29.2%vs 32.0%)。结论维持性血液透析患者肌少症患病率较高,需开展干预研究。Objective To systematically evaluate the prevalence of sarcopenia in maintenance hemodialysis patients.Methods A comprehensive search of Chinese and English databases including CNKI,China Biomedical Literature Database(CBM),Wanfang Data,Vipers Database(VIP),Pubmed,Embase,web of science,EBSCO was conducted to identify related studies on the prevalence of sarcopenia in maintenance hemodialysis patients.The included literature was screened,the required data were extracted,and the quality of the literature was evaluated strictly according to the criteria.Meta-analysis was performed by Stata 12.0 software.Results In this study,a total of 15 articles were included with middle to high quality,involving 2 561 maintenance hemodialysis patients.Results of the meta-analysis showed that the prevalence of sarcopenia in maintenance hemodialysis patients was 31.2%(95%CI:24.9%-37.6%),and that in Asian patients was 31.0%(95%CI:22.9%-39.1%).The prevalence of sarcopenia was higher in men than in women(37% vs 28%),and the prevalence of sarcopenia using AWGS was higher than that using EWGSOP(36.8% vs 26.2%).The prevalence of sarcopenia using DEXA was slightly lower than that using BIA(29.2% vs 32.0%).Conclusion The prevalence of sarcopenia in maintenance hemodialysis patients is high and intervention studies are needed.

关 键 词：血液透析 肌少症 META分析 

分 类 号：R692.5[医药卫生—泌尿科学] R685[医药卫生—外科学]