基于纯化学位移的同核二维正交相敏J分解核磁共振波谱  

Two-Dimensional Homonuclear Orthogonal-Pattern Phase-Sensitive J-Resolved NMR Spectroscopy Based on Pure Shifts

作　　者：林晓晴 杜世佳 詹昊霖 黄玉清[1] 陈忠[1] LIN Xiao-qing;DU Shi-jia;ZHAN Hao-lin;HUANG Yu-qing;CHEN Zhong(Department of Electronic Science,Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance,Xiamen University,Xiamen 361005,China)

机构地区：[1]厦门大学电子科学系,福建省等离子体与磁共振研究重点实验室,福建厦门361005

出　　处：《波谱学杂志》2021年第4期448-459,共12页Chinese Journal of Magnetic Resonance

基　　金：国家自然科学基金资助项目(U1805261,22073078,U1632274,11675135和11761141010).

摘　　要：二维J分解(2D JRES)核磁共振(NMR)波谱是一种简单且用户友好的谱图表达形式,其将J偶合常数和化学位移信息分离到两个正交的频率维度上.自40年前首次被提出以来,2D JRES技术在脉冲序列和方法的改进,以及实际应用的进展方面一直备受关注.本文回顾了新型2D JRES脉冲序列,以及用于精确测量同核J偶合常数的2D J编辑谱的最近进展,特别是基于纯化学位移演化机制的正交相敏2D JRES谱方法及其应用,并阐述其在克服强偶合效应和磁场不均匀性等方面的能力.Two-dimensional J-resolved(2D JRES)nuclear magnetic resonance(NMR)experiments provide a simple and user-friendly spectral representation,in which J couplings and chemical shifts are separated into two orthogonal frequency dimensions.The 2D JRES experiments have attracted wide attention in fundamental pulse sequence developments and practical applications,since they were first proposed 40 years ago.In this paper,we review the recent advances in the development of novel 2D JRES pulse sequences and 2D J-edited methods for accurate measurements of J coupling,mainly focusing on pure shift based 2D orthogonal-pattern and phase-sensitive 2D JRES spectroscopy and their applications in overcoming strong coupling effects and field inhomogeneities.

关 键 词：核磁共振 J分解谱 相敏 G-SERF J偶合常数 纯化学位移 

分 类 号：O482.53[理学—固体物理]