双清消斑饮对痰瘀互结型稳定性心绞痛患者心肺运动试验结果及生活质量的影响  

Effect of Shuangqing Xiaoban Decoction on the Results of Cardiopulmonary Exercise Testing and Quality of Life in Patients Diagnosed as Stable Angina with the Syndrome of Phlegm and Bloom Stasis

作　　者：王婷[1] 熊尚全[1] 林超[1] 詹萍[1] 乔建峰[1] WANG Ting;XIONG Shangquan;LIN Chao;ZHAN Ping;QIAO Jianfeng(People’s Hospital Affiliated to Fujian University of Traditional Chinese Medicine,Fuzhou 350004,China;不详)

机构地区：[1]福建中医药大学附属人民医院,福建福州350004

出　　处：《中外医学研究》2021年第31期13-17,共5页CHINESE AND FOREIGN MEDICAL RESEARCH

基　　金：福建省中青年教师教育科研项目(2020-039-02)。

摘　　要：目的:观察双清消斑饮对痰瘀互结型稳定性心绞痛患者心肺运动试验结果及生活质量的影响。方法:收集2020年1-6月在福建中医药大学附属人民医院就诊的痰瘀互结型稳定性心绞痛患者70例,按随机数字表法分为对照组和治疗组,各35例。对照组参照2018年《稳定性冠心病诊断与治疗指南》推荐的药物治疗方案治疗,治疗组在对照组基础上加用双清消斑饮治疗,两组观察期均为3个月,两组患者治疗前后分别进行心肺运动试验(cardiopulmonary exercise testing,CPET),记录峰值摄氧量(peak VO_(2))、无氧阈值(AT)、峰值氧脉搏(VO_(2)/HR)、二氧化碳通气当量最低值(VE/VCO_(2)最低值)、二氧化碳通气当量斜率(VE/VCO_(2)斜率)等指标;采用SAQ、SF-36量表在治疗前后分别对两组患者进行调查。结果:两组治疗前心肺运动试验各观察指标比较差异无统计学意义(P>0.05);治疗后两组peak VO_(2)、AT、VO_(2)/HR均升高,且治疗组高于对照组(P<0.05);两组VE/VCO_(2)最低值、VE/VCO_(2)斜率均下降,且治疗组低于对照组(P<0.05);治疗组SAQ、SF-36评分高于对照组(P<0.05)。结论:联合使用双清消斑饮能进一步改善痰瘀互结型稳定性心绞痛患者心肺功能及生活质量,治疗效果好。Objective:To observe the effect of Shuangqing Xiaoban Decoction on the results of cardiopulmonary exercise testing and quality of life in the patients diagnosed as stable coronary heart disease with the syndrome of phlegm and bloom stasis.Method:Seventy subjects of this study diagnosed as stable coronary heart disease with the syndrome of phlegm and bloom stasis who were admitted in People’s Hospital Affiliated to Fujian University of Traditional Chinese Medicine from January to June 2020 were randomly divided into the control group and the treatment group,with 35 cases in each group.The patients in the control group were treated according to the treatment plan recommended by the Guidelines for the Diagnosis and Treatment of Stable Coronary Heart Disease in 2018,and the patients in the treatment group received Shuangqing Xiaoban Decoction treatment in addition to the basic drug treatment.The observation period was three months in both two groups.All patients were surveyed by cardiopulmonary exercise testing with the indexes recorded,including the peak oxygen uptake(peak VO_(2)),anaerobic threshold(AT),peak oxygen pulse(VO_(2)/HR),the lowest value of carbon dioxide ventilation equivalent(the lowest value of VE/VCO_(2)),and the slope of carbon dioxide equivalent ventilation(VE/VCO_(2)slope).SAQ and SF-36 scales were used to investigate the two groups of patients before and after treatment.Result:There were no significant differences in the indexes between the two groups before treatment(P>0.05).After treatment,compared with those of the patients in the control group,the levels of peak VO_(2),AT and VO_(2)/HR in the treatment group were higher,and the treatment group’s indexes were higher than those in the control group,the difference were statistically significant(P<0.05).While the levels of the lowest value of VE/VCO_(2)and the VE/VCO_(2)slope were lower,and the treatment group’s indexes were lower than those in the control group,the differences were statistically significant(P<0.05).The SAQ and SF-36 in tre

关 键 词：稳定性心绞痛 痰瘀互结 双清消斑饮 心肺运动试验 生活质量 

分 类 号：R541.4[医药卫生—心血管疾病]