高压氧与维生素E治疗成年特发性少精弱精症对比研究  

Comparative Study of Hyperbaric Oxygen and Vitamin E in the Treatment of Adult Idiopathic Oligospermia and Asthenospermia

作　　者：陈颖 郑志涛 CHEN Ying;ZHENG Zhitao(Songshanhu Central Hospital,Dongguan City,Dongguan 523000,China;不详)

机构地区：[1]东莞市松山湖中心医院,广东东莞523000

出　　处：《中外医学研究》2021年第31期37-40,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

基　　金：东莞市社会科技发展(一般)项目(2018507150241545)。

摘　　要：目的:对比研究高压氧与维生素E治疗成年特发性少精弱精症的临床效果。方法:将2018年6月-2020年12月本院收治的80例特发性少精弱精症患者作为研究对象。随机分为两组,将使用维生素E治疗的40例患者作为对照组,将使用高压氧治疗的40例患者作为观察组。对比分析两组患者治疗前后精子密度、精子活力、精子活率及液化时间,研究两组患者临床疗效及治疗期间不良反应发生状况。结果:观察组总有效率显著高于对照组,差异有统计学意义(P<0.05)。治疗前,两组精子密度、精子活力、精子活率及液化时间对比,差异无统计学意义(P>0.05);治疗1个月后,两组精子活力、精子活率均升高,且观察组高于对照组,两组液化时间均缩短,且观察组短于对照组,差异均有统计学意义(P<0.05);两组精子密度均显著高于治疗前(P<0.05),观察组略高于对照组,但组间比较差异无统计学意义(P>0.05)。观察组不良反应总发生率略低于对照组,但组间比较差异无统计学意义(P>0.05)。结论:高压氧治疗成年特发性少精弱精症具有显著效果,能够改善精子质量,适用于临床。Objective:To compare the clinical effect of hyperbaric oxygen and Vitamin E in the treatment of adult idiopathic oligospermia and asthenospermia.Method:A total of 80 patients with idiopathic oligozoospermia and asthenospermia in our hospital from June 2018 to December 2020 were selected as the research objects.They were randomly divided into two groups,40 patients treated with Vitamin E as the control group and 40 patients treated with hyperbaric oxygen as the observation group.The sperm density,sperm motility,sperm motility and liquefaction time of the two groups before and after treatment were compared and analyzed,and the clinical efficacy and adverse reactions of the two groups during treatment were studied.Result:The total effective rate of the observation group was significantly higher than that of the control group,the difference was statistically significant(P<0.05).Before treatment,there were no significant differences in sperm density,sperm motility,sperm motility and liquefaction time between the two groups(P>0.05).After one month of treatment,the sperm motility and sperm motility rate of the two groups increased,and the observation group’s were higher than those of the control group,the liquefaction time of the two groups were shorten,and the observation group was shorter than that in the control group,the differences were statistically significant(P<0.05);the sperm density of the two groups were significantly higher than that before treatment(P<0.05),but there was no significant difference between the two groups after treatment(P>0.05).The total incidence of adverse reactions in the observation group was slightly lower than that in the control group,but there was no statistically significant difference(P>0.05).Conclusion:Hyperbaric oxygen treatment of adult idiopathic oligozoospermia and asthenospermia has significant effect,can improve sperm quality,suitable for clinical application.

关 键 词：少精弱精症 高压氧 维生素E 精子密度 精子液化时间 

分 类 号：R698.2[医药卫生—泌尿科学]