新生儿胃肠外营养相关性胆汁淤积的危险因素研究  

Research of the Risk Factors of Newborn Parenteral Nutrition Associated Cholestasis

作　　者：孙小卉 Sun Xiaohui(Dingxi People’s Hosptial, Dingxi 743000, China)

机构地区：[1]定西市人民医院,甘肃定西743000

出　　处：《黑龙江科学》2021年第22期62-63,共2页Heilongjiang Science

摘　　要：探讨新生儿胃肠外营养相关性胆汁淤积(parenteral nutrition associated cholestasis,PNAC)的相关危险因素,以降低新生儿发生PNAC的风险。选取胃肠外营养治疗的80例新生患儿,根据是否发生PNAC分为PNAC组和非PNAC组,比较所有患儿胃肠外营养干预后各项指标的差异并找出相关的潜在危险因素。与非PNAC组新生患儿相比,PNAC组患儿的胃肠外营养持续时间及禁食时间均有显著升高,氨基酸及脂肪乳提供热量的比率也有显著升高,总热量显著降低(P<0.05),差异均有统计学意义。新生儿发生PNAC的危险因素主要与以下几个指标有关系,即:胃肠外营养持续时间、禁食时间、新生儿体重和氨基酸脂肪乳热量比率。掌握了这些临床独立因素,就能够在一定程度上降低新生儿发生PNAC的概率。The research explores the newborn parenteral nutrition associated cholestasis(PNAC)to reduce the risks of newborn PNAC.80 newborn patients who receive parenteral nutrition are selected,and they are divided into PNAC group and non PNAC group.Difference of all indexes after parenteral nutrition intervention is compared,and the related potential risk factors are found.Compared with newborn patients of non PNAC group,parenteral nutrition duration time and abrosia of PNAC group increase,heat rate provided by amino acid and fat emulsion increase significantly,and the total heat decreases,with statistically significant difference(P<0.05).The risk factors related with newborn PNAC are mainly related with the following indexes,i.e.parenteral nutrition duration;ambrosia time,newborn weight and amino acid fat emulsion heat rate.The grasp of these clinical independent factors can decrease newborn PNAC occurrence rate to some extent.

关 键 词：新生儿胃肠外营养相关性胆汁淤积 危险因素 临床研究 

分 类 号：R723[医药卫生—儿科]