SAPHO综合征合并慢性扁桃体炎1例报告并文献复习  

SAPHO syndrome with chronic tonsillitis: a case report and literature review

作　　者：贾慧 李勇[1] 刘增平[1] 郭玉芬[1] JIA Hui;LI Yong;LIU Zengping

机构地区：[1]兰州大学第二医院耳鼻咽喉头颈外科,兰州730030

出　　处：《临床耳鼻咽喉头颈外科杂志》2021年第10期944-947,共4页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

基　　金：国家自然科学基金面上项目(No:81570926)。

摘　　要：SAPHO综合征是包含滑膜炎(synovitis)、痤疮(acne)、脓疱病(pustulosis)、骨肥厚(hyperotosis)及骨炎(osteitis)的一种罕见的炎症性疾病,常累及骨、关节和皮肤[1]。因其临床症状可能不会同时出现,且个体表现差异很大,常被单独诊断为皮肤、关节、脊柱或其他系统疾病[2]。目前尚无统一的治疗指南,医生普遍采用经验性的治疗缓解临床症状。我科以慢性扁桃体炎收治1例SAPHO综合征患者,现报告如下。SAPHO syndrome is a rare disease which affects the bones, joints, and skin. It is often misdiagnosed and treated mistakenly because of various clinical manifestations and general lack of awareness about the disease. The pathogenesis is inadequately understood, as a result, current therapy is empirical and aimed to control inflammatory process and alleviate pain. This paper summarizes the clinical manifestations and diagnosis and treatment scheme of SAPHO syndrome, and presents a case of patient with SAPHO syndrome who was treated in our department for bilateral tonsillectomy due to repeated pharyngalgia and fever for 10 years. Interestingly, the patient is getting better after the operation. The case is reported so as to provide reference for the diagnosis and treatment of SAPHO syndrome.

关 键 词：SAPHO综合征 脓疱病 骨肥厚 扁桃体炎 

分 类 号：R766[医药卫生—耳鼻咽喉科]