脉冲射频治疗膝关节骨性关节炎临床疗效的Meta分析  

Clinical efficacy of pulsed radiofrequency in the treatment of knee osteoarthritis:a meta-analysis

作　　者：李远栋[1] 卜寒梅 王平[1] 崔中赏 张超[1] 刘爱峰[1] Li Yuandong;Bu Hanmei;Wang Ping;Cui Zhongshang;Zhang Chao;Liu Aifeng(Orthopedics and Traumatology,First Teaching Hospital of Tianjin University of Traditional Chinese Medicine,Regional TCM bone injury diagnosis and treatment center of State Administration of Traditional Chinese Medicine,National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion,Tianjin 300381,China)

机构地区：[1]天津中医药大学第一附属医院骨伤科,国家中医药管理局区域中医骨伤诊疗中心,国家中医针灸临床医学研究中心,300381

出　　处：《国际生物医学工程杂志》2021年第4期266-271,共6页International Journal of Biomedical Engineering

基　　金：天津市教委科研计划项目(2019KJ064);国家自然科学基金项目(81873316,82074470,81102607,81673994,51573137);王平劳模创新工作室-天津市教委资助项目(2016-3);中医传承工作室-天津卫计委资助项目(2017-193)。

摘　　要：目的采用Meta分析方法评价脉冲射频(PRF)治疗膝关节骨性关节炎(KOA)的临床疗效。方法检索PRF治疗KOA的临床对照研究文献,检索数据库包括:中国生物医学文献数据库、The Cochrane Library、PubMed、Web of Science、Medline、EMBASE、中国知网、万方数据库、维普数据库、CBM、EBSCO及网络数据库,文献检索时间范围:建库时间至2021年2月。由2名研究者对检索到的文献进行筛选、质量评价及数据提取,使用Review Manager 5.3软件进行统计学分析。结果共纳入8项研究,包括411例KOA患者,其中试验组(PRF治疗)200例,对照组(常规治疗)211例。Meta分析结果表明,试验组在膝关节VAS评分、WOMAC评分、Lysholm评分和有效率方面均优于对照组,差异具有统计学意义(均P<0.05)。结论PRF治疗KOA的效果确切,优于常规治疗。本研究符合纳入标准的文献研究质量偏低,未来仍需开展大量的高质量研究对其疗效及安全性进行评价。Objective To evaluate the clinical efficacy of pulsed radio-frequency(PRF)for knee osteoarthritis(KOA)using Meta-analysis.Methods The literature of controlled clinical studies on PRF in the treatment of KOA was retrieved,the retrieval databases included China Biomedical Literature Database,The Cochrane Library,PubMed,Web of Science,Medline,Embase,CNKI,Wanfang Database,VIP Database,CBM,EBSCO and Network database.The retrieval period was the time of inception to February 2021.The retrieved literature was screened,quality evaluated and data extracted by two researchers.Statistical analysis was performed using Review Manager 5.3 software.Results A total of 8 studies were included,including 411 patients with KOA.The 200 patients in the trial group were underwent PRF treatment and the 211 patients in the control group were underwent conventional treatment.Meta-analysis results showed that the experimental group was superior to the control group in terms of knee VAS score,WOMAC score,Lysholm score and effective rate,and the differences were statistically significant(all P<0.05).Conclusions PRF is more effective in treating KOA than conventional treatment.The quality of the literature research in this study that met the inclusion criteria was low,and a large number of high-quality studies are needed to evaluate the efficacy and safety of PRF treatment.

关 键 词：脉冲射频 膝关节骨性关节炎 临床疗效 META分析 

分 类 号：R684.3[医药卫生—骨科学]