聚合物微针载药系统研究进展  

Research progress on microneedle drug delivery systems

作　　者：陈怡[1] 宋婷[1] 陈雯琳 李海梁 卢爱玉 张峻颖[1] CHEN Yi;SONG Ting;CHEN Wenlin;LI Hailiang;LU Aiyu;ZHANG Junying(Department of TCMs Pharmaceuticals,China Pharmaceutical University,Nanjing 211198,China)

机构地区：[1]中国药科大学中药制药系,江苏南京211198

出　　处：《药学研究》2021年第11期744-747,767,共5页Journal of Pharmaceutical Research

基　　金：国家自然科学基金资助项目(No.81473357)。

摘　　要：微针是一种新型的透皮给药剂型,它通过特殊的针状结构在皮肤表面形成微小孔道以突破皮肤的屏障,从而将药物高效地递送到体内发挥药效。近些年来,微针的研究取得了重大的成果,本文综述了近五年来聚合物微针载药系统的研究成果,并对其研究前景进行了展望。Microneedle is a new type of transdermal drug delivery formulations,which form tiny pores on the surface of the skin through a special needle-like structure to break through the barrier of the skin and efficiently deliver drugs.In recent years,the research of microneedles has achieved a lot.This review summarized the latest research progress and outlines the prospects for microneedle drug delivery systems.

关 键 词：微针 经皮给药 载药系统 

分 类 号：R943[医药卫生—药剂学]