微创前外侧入路下全髋置换术治疗股骨颈骨折患者的临床效果  

Clinical Effect of Minimally Invasive Anterior Lateral Approach for Total Hip Replacement in Patients with Femoral Neck Fractures

作　　者：张晓冬 白小岗[2] 李延军 ZHANG Xiaodong;BAI Xiaogang;LI Yanjun(Tibet Fukang Hospital,Lhasa 850000,China;不详)

机构地区：[1]西藏阜康医院,西藏拉萨850000 [2]延安大学附属医院

出　　处：《中外医学研究》2021年第33期40-43,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:研究微创前外侧入路下全髋置换术治疗股骨颈骨折患者的临床效果。方法:选取2018年6月-2020年12月在本院进行治疗的60例股骨颈骨折患者,按照随机数字表法将其分为对照组和试验组,每组30例。对照组行微创前外侧入路下半髋置换术,试验组行微创前外侧入路下全髋置换术。比较两组手术情况,比较两组术前与术后25 d疼痛介质指标[前列腺素E;(PGE;)、5-羟色胺(5-HT)]和骨代谢指标[骨特异性碱性磷酸酶(BAP)、骨钙素(BGP)、Ⅰ型胶原羧基端前肽(PⅠCP)]。结果:试验组手术时间长于对照组,差异有统计学意义(P<0.05)。两组切口长度、出血量比较,差异均无统计学意义(P>0.05)。术前,两组PGE;、5-HT、BGP、PⅠCP、BAP水平比较,差异均无统计学意义(P>0.05);术后25 d,两组PGE;、5-HT水平均低于术前,BGP、PⅠCP、BAP水平均高于术前,且试验组PGE;、5-HT水平均低于对照组,BGP、PⅠCP、BAP水平均高于对照组,差异均有统计学意义(P<0.05)。结论:微创前外侧入路下全髋置换术可缓解股骨颈骨折患者术后疼痛,加快骨代谢,从而促进患肢功能恢复,应用效果显著。Objective:To investigate the clinical effect of minimally invasive anterior lateral approach for total hip replacement in patients with femoral neck fracture.Method:A total of 60 patients with femoral neck fracture treated in our hospital from June 2018 to December 2020 were selected,and they were divided into control group and experimental group according to random number table method,30 cases in each group.The control group received minimally invasive anterior lateral approach for lower hip replacement,while the experimental group received minimally invasive anterior lateral approach for total hip replacement.The surgery conditions was compared between two groups,pain mediators[prostaglandin E;(PGE;),5-hydroxytryptophan(5-HT)]and bone metabolism indexes[bone-specific alkaline phosphatase(BAP),osteocalcin(BGP),typeⅠcollagen carboxy-terminal propeptide(PⅠCP)]before and 25 d after surgery were compared between two groups.Result:The surgical time in the experimental group was longer than that in the control group,and the difference was statistically significant(P<0.05).There were no significant differences in incision length and blood loss between two groups(P>0.05).Before surgery,there were no significant differences in the levels of PGE;,5-HT,BGP,PⅠCP and BAP between two groups(P>0.05);25 d after surgery,the levels of PGE;and 5-HT in both groups were lower than those before surgery,and the levels of BGP,PⅠCP and BAP were higher than those before surgery,the levels of PGE;and 5-HT in the experimental group were lower than those in the control group,and the levels of BGP,PⅠCP and BAP in the experimental group were higher than those in the control group,the differences were statistically significant(P<0.05).Conclusion:Minimally invasive anterolateral approach for total hip replacement alleviates postoperative pain and accelerates bone metabolism in patients with femoral neck fractures,thereby promoting functional recovery of the affected limb,the application effect was remarkable.

关 键 词：股骨颈骨折 微创前外侧入路下全髋置换术 微创前外侧入路下半髋置换术 

分 类 号：R687.4[医药卫生—骨科学]