心脏磁共振T_(2)-mapping定量技术在急性心肌炎诊断中的应用价值  

The value of cardiac magnetic resonance quantitative T_(2)-mapping technique in the diagnosis of acute myocarditis

作　　者：熊俊峰[1] 朱希松[1] 江朝根[1] 徐亮 何小龙 王春艳 王远成 XIONG Junfeng;ZHU Xisong;JIANG Chaogen;XU Liang;HE Xiaolong;WANG Chunyan;WANG Yuancheng(Department of Radiology,Quzhou People's Hospital,Quzhou 324000,China)

机构地区：[1]衢州市人民医院放射科,324000 [2]东南大学附属中大医院放射科

出　　处：《心电与循环》2021年第6期590-593,共4页Journal of Electrocardiology and Circulation

基　　金：衢州市科技计划指导项目(2021004)。

摘　　要：目的探讨心脏磁共振T_(2)-mapping定量技术在急性心肌炎诊断中的应用价值。方法选择2015年4月至2020年9月在衢州市人民医院就诊的急性心肌炎患者(观察组)74例,选择同期50例健康体检者作为健康对照组,两组对象均接受心脏磁共振常规检查、T_(2)-mapping序列成像、延迟增强(LGE)扫描,比较两组患者心功能参数和T2值。根据延迟增强检查结果将患者分为LGE亚组和无LGE亚组,比较两亚组与健康对照组T_(2)值差异。分析急性心肌炎患者T_(2)值与肌钙蛋白I(cTnI)、肌钙蛋白T(cTnT)、肌酸激酶同工酶(CK-MB)的关系。结果观察组左心室舒张末期容积与容积指数、左心室收缩末期容积与容积指数、每搏量、每搏量指数和T2值高于健康对照组,差异均有统计学意义(均P<0.05)。LGE亚组和无LGE亚组T2值均高于健康对照组,LGE亚组T_(2)值均高于无LGE亚组,差异均有统计学意义(均P<0.05);急性心肌炎患者T_(2)值与cTnI、cTnT、CK-MB水平呈正相关(r=0.513、0.522、0.558,均P<0.05)。结论心脏磁共振T_(2)-mapping定量技术可用于急性心肌炎的诊断和心肌损伤程度的评估。Objective To investigate the value of cardiac magnetic resonance(MRI)quantitative T_(2)-mapping technique in the diagnosis of acute myocarditis.Methods A total of 74 patients with acute myocarditis fromApril 2015 to September 2020 in Quzhou People's Hospital were selected as observation group,and 50 healthy people were selected as control group.All subjects underwent routine cardiac MRI,T_(2)-mapping sequence imaging and late gadolinium enhancement(LGE)scan.Cardiac function parameters and T_(2) value were compared between the two groups.According to the results of LGE,the patients were divided into LGE group and non-LGE group.T_(2) values were compared between groups.The relationship of T_(2) value to cardiac troponin I(cTnI),cardiac troponin T(cTnT)and creatine kinase MB(CK-MB)in patients with acute myocarditis was analyzed.Results Left ventricular end diastolic volume and end diastolic volume index,left ventricular end systolic volume and end systolic volume index,stroke volume,stroke volume index and T_(2) value were significantly higher in the observation group than in the control group(all P<0.05).The T_(2) value was significantly higher in both LGE group and non-LGE group than in the control group,and was significantly higher in LGE group than in non-LGE group(all P<0.05).There was a positive correlation between T_(2) value and cTnI,cTnT and CK-MB in patients with acute myocarditis(r=0.513,0.522,0.558,all P<0.05).Conclusion Cardiac magnetic resonance quantitative T_(2)-mapping technique can be used for the diagnosis of acute myocarditis and assessment of myocardial injury degree.

关 键 词：心脏磁共振 急性心肌炎 T_(2)-mapping 序列成像 心肌损伤 

分 类 号：R542.21[医药卫生—心血管疾病] R445.2[医药卫生—内科学]