Sysmex XN-9000复检规则及3R规则在综合医院应用中的评估  

Evaluation of the Review Rules and 3R Rules for Sysmex XN-9000 in General Hospitals

作　　者：王小华[1] WANG Xiaohua(Department of Clinical Laboratory,the Nanping First Hospital of FuJian Medical University,Nanping 353000,China)

机构地区：[1]福建医科大学附属南平市第一医院检验科,福建南平353000

出　　处：《中国医药指南》2021年第34期35-37,共3页Guide of China Medicine

摘　　要：目的建立本实验室的Sysmex XN-9000全自动血细胞分析流水线的复检规则及3R规则并进行验证评估,以提高工作质量和效率。方法依据国际血液学学会推荐的"41条自动CBC和DC复检规则"和国内XE-2100血液分析仪复检标准制定协作组推荐的"23条复检规则"及XN-9000的性能初步建立本实验室的复检规则及3R规则,在此规则指导下对1 032例样本进行分析,统计涂片复检率,对此规则进行评估并不断优化,规则建立后,选择500例样本(主要为血液病和肿瘤化疗患者病例)进行验证,评价规则的可行性和有效性。结果初步建立了本实验室24条血常规复检规则及Sysmex XN-9000的11条3R规则,对评估检测结果进行统计分析,真阳性率21.70%(224例),假阳性4.85%(50例),真阴性72.00%(743例),假阴性1.45%(15例),无病理性细胞漏检。对验证检测结果进行统计分析,结果显示准确率为93.70%;推片复检率为18.99%(196例),假阳性率4.00%(20例),假阴性3.00%(15例)。结论Sysmex XN-9000复检规则及3R规则规则下假阴性率为3.00%,符合国际规定的标准(小于5.00%),该规则有效地提高了检测效率,减少了漏检率及误检率,符合本实验室质量及工作效率的要求。Objective To establish the review rules and 3 R rules of Sysmex XN-9000 automatic blood cell analysis in laboratory, to improve the quality and efficiency of the work. Methods According to "the 41 CBC and DC Items of International Review Rules", "the 23 Reviews Rules" of the domestic XE-2100 blood analyzer review standards group recommended and the performance of XN-9000, the individualization review rules and 3 R rules were established.The rules were optimized by the statistical smear rate with the instrument and microscopic examination results of the 1032 samples. Select 500 samples(mainly for blood disease and tumor chemotherapy patients) to verify the feasibility and reliability of the evaluation rules. Results The 3 R rules and review rules were established for the laboratory. The examination results carried on the statistical analysis, it was positive in 224 cases(21.70%), 50 cases of false positive(4.85%), true negative in 743 cases(72.00%), 15 cases of false negative(1.45%), no blood cell disease detection. The results showed that the accuracy rate was 93.70%, and the 196 cases(18.99%) needed to be reexamined. The false positive rate was 4.00%(20 cases) and false negative rate was 3.00%(15 cases).Conclusion The false negative rate of 3% is less than 5% of the Sysmex XN-9000 review rules and 3 R rules. This rules can not only improve the detection efficiency, but also prevent the omission and false detection.

关 键 词：Sysmex XN-9000 复检规则 3R规则 涂片复检率 假阴性率 

分 类 号：R446.11[医药卫生—诊断学]