内镜下注射硬化剂聚桂醇治疗消化性溃疡出血的效果观察  

Therapeutic effect of endoscopic injection of sclerosing agent lauromacrogol on peptic ulcer with hemorrhage

作　　者：刘礼剑[1] 黄晓燕[1] 韦金秀 杨成宁 陈广文[1] 李建锋 刘莉[1] 赵一娜[1] 卢杰夫[1] LIU Li-jian;HUANG Xiao-yan;WEI Jin-xiu;YANG Cheng-ning;CHEN Guang-wen;LI Jian-feng;LIU Li;ZHAO Yi-na;LU Jie-fu(Department of Spleen and Stomach Diseases,the First Affiliated Hospital of Guangxi University of Chinese Medicine,Nanning 530023,China)

机构地区：[1]广西中医药大学第一附属医院脾胃病科,南宁市530023

出　　处：《广西医学》2021年第19期2276-2278,共3页Guangxi Medical Journal

基　　金：广西自然科学基金(2018GXNSFBA281130);广西科技计划(桂科AD19245168);中医药循证能力建设项目(2019XZZX-XH003)。

摘　　要：目的观察内镜下注射硬化剂聚桂醇治疗消化性溃疡出血的临床效果。方法将100例消化性溃疡出血的患者随机分为观察组与对照组,每组50例。观察组给予内镜下注射硬化剂聚桂醇治疗,对照组患者给予内镜下注射肾上腺素治疗。比较两组患者的即时止血率、转手术率、再出血率、止血时间、住院时间、住院费用及不良反应发生率。结果观察组的即时止血率高于对照组,再出血率、止血时间、住院时间均低于或短于对照组,住院费用少于对照组(均P<0.05),但两组转手术率差异无统计学意义(P>0.05)。结论内镜下注射聚桂醇治疗消化性溃疡出血患者可提高即时止血率,降低再出血率,缩短止血时间和住院时间,减少住院费用。Objective To observe the clinical efficacy of endoscopic injection of sclerosing agent lauromacrogol for the treatment of peptic ulcer with hemorrhage.Methods A total of 100 patients with peptic ulcer with hemorrhage were randomly divided into observation group and control group,with 50 cases in each group.The observation group was treated with endoscopic injection of sclerosing agent lauromacrogol,whereas the control group was treated with endoscopic injection of epinephrine.The immediate hemostasis rate,the rate of conversion to operation,the re-bleeding rate,hemostasis time,hospital stay,hospitalization costs,and the incidence rate of adverse reactions were compared between the two groups.Results The observation group exhibited a higher immediate hemostasis rate,a lower re-bleeding rate,shorter hemostasis time and hospital stay,and decreased hospitalization costs as compared with the control group(all P<0.05),but there was no statistically significant difference in the rate of conversion to operation between the two groups(P>0.05).Conclusion Endoscopic injection of lauromacrogol can increase the immediate hemostasis rate,reduce the re-bleeding rate,shorten hemostasis time and hospital stay,and decrease hospitalization costs in the treatment of patients with peptic ulcer with hemorrhage.

关 键 词：消化性溃疡出血 聚桂醇 肾上腺素 止血 再出血 内镜治疗 

分 类 号：R656.1[医药卫生—急诊医学]