糖基氮杂环卡宾钯催化Suzuki反应研究  

Glucopyranoside-NHCs-Pd Complexes for Efficient Suzuki Reaction

作　　者：张旻杰[1,2] 刘红波[1,2] 戚琦[1,2] 林芳 周玥龙 周中高 ZHANG Minjie;LIU Hongbo;QI Qi;LIN Fang;ZHOU Yuelong;ZHOU Zhonggao(School of Chemistry&Chemical Engineering,Gannan Normal University,Ganzhou 341000,China;Key Laboratory of Jiangxi University for Functional Material Chemistry,Gannan Normal University,Ganzhou 341000,China)

机构地区：[1]赣南师范大学化学化工学院,江西赣州341000 [2]赣南师范大学,江西省高校功能材料化学重点实验室,江西赣州341000

出　　处：《赣南师范大学学报》2021年第6期43-48,共6页Journal of Gannan Normal University

基　　金：国家自然科学基金资助项目(21967002,21562002);研究生创新基金项目(YCX20A008);江西省教育厅基金(GJJ201427);研究生优质课程项目。

摘　　要：以D-葡萄糖为起始原料,经4步反应,合成了2种氮杂环卡宾吡啶配位钯络合物[1-(2,3,4,6-四-O-乙酰基-β-D-吡喃葡萄糖基)-3-甲基-咪唑啉-2-亚基-溴化钯(Ⅱ)-吡啶和1-(2,3,4,6-四-O-乙酰基-β-D-吡喃葡萄糖基)-3-正丁基-咪唑啉-2-亚基-溴化钯(Ⅱ)-吡啶].这两种结构新颖的钯络合物,在水溶液中能够快速催化Suzuki偶联反应,仅使用0.05 mol%催化剂用量,就能取得优异的收率.Two glucopyranoside-functionalized N-heterocyclic carbene Pd(Ⅱ)-PEPPSI complexes([1-(2-β-D-glucopyranosyloxyethyl)-3-methyl-imidazol-ylidene]Pd(pyridine)Br 2 and[1-(2-β-D-glucopyranosyloxyethyl)-3-butyl-imidazol-ylidene]Pd(pyridine)Br 2)were synthesized from D-glucose through four steps of reaction.These Glu-NHCs-Pd(Ⅱ)-PEPPSI complexes were used as high-efficiency catalyst for the Suzuki coupling reaction in the ethanol aqueous,and excellent yields can be achieved with 0.05 mol%catalyst loading.

关 键 词：碳水化合物 氮杂环卡宾 钯络合物 SUZUKI反应 绿色化学 

分 类 号：O482.53[理学—固体物理]