动脉粥样硬化及缺血性心肌损伤相关炎症机制的研究进展  

Research progress of atherosclerosis and ischaemic myocardial injury-related inflammatory mechanism

作　　者：于雪莲 李香 YU Xue-lian;LI Xiang(Department of Cardiology,Yanbian University Hospital,Yanji 133000,China)

机构地区：[1]延边大学附属医院心血管内科,吉林省延吉市133000

出　　处：《中国心血管病研究》2021年第11期1039-1043,共5页Chinese Journal of Cardiovascular Research

基　　金：国家自然科学基金资助项目(82060052)。

摘　　要：目前对于动脉粥样硬化(AS)的看法发生了深刻的变化,研究认为动脉粥样硬化不单纯是脂质沉积异常,而是全身性炎性反应,有炎性因子及免疫细胞参与。炎性因子在动脉粥样硬化的形成、发展中具有重要作用,最终导致缺血性心肌损伤。本文就近年有关冠状动脉粥样硬化及其所致的缺血性心肌损伤相关炎性因子的研究进展作简要概述。At present, the perception of atherosclerosis(AS) has undergone profound changes. It is believed that atherosclerosis is no longer simply an abnormal lipid deposition, but a systemic inflammatory response, which includes the participation of inflammatory factors and immune cells. Inflammatory mechanisms play an important role in the formation and development of atherosclerosis, eventually lead to ischaemic myocardial Injury. This paper briefly summarizes the research progress of coronary atherosclerosis and ischaemic myocardial injury-related inflammatory mechanisms in recent years.

关 键 词：动脉粥样硬化 缺血性心肌损伤 炎性因子 免疫细胞 

分 类 号：R541.4[医药卫生—心血管疾病]