手性的控制:不对称有机催化——2021年诺贝尔化学奖成果简析  

Chiral chemistry:Asymmetric organocatalysis:The 2021 Nobel Prize in Chemistry

作　　者：李桂根 LI Guigen(Institute of Chemistry and BioMedical Sciences,School of Chemistry and Chemical Engineering,Nanjing University,Nanjing 210093,China;Department of Chemistn-and Biochemistry,Texas Tech University,Lubbock 79409,USA)

机构地区：[1]南京大学化学化工学院化学与生物医学科学研究所,南京210093 [2]美国德州理工大学化学与生物化学系,拉伯克79409

出　　处：《科技导报》2021年第22期120-129,共10页Science & Technology Review

摘　　要：2021年诺贝尔化学奖授予德国化学家Benjamin List和苏格兰裔美英籍化学家David MacMillan,以表彰他们在不对称有机催化领域的贡献。介绍了该诺奖工作的源头创新点和背景。阐述了手性化学、手性催化剂和不对称有机催化,及其对手性的控制。概括了有机催化和催化剂的类别。介绍了中国科学家和华人科学家在有机不对称催化领域的重要贡献,并对该领域的发展、研究现状和未来进行了展望。The 2021 Nobel Prize in Chemistry has been awarded to two chemists,Benjamin List and David W.C.MacMillan for their contributions"for the development of asymmetric organocatalysis".This paper reviews the source,the innovation and the background of the Nobel prize work.The chiral chemistry,the chiral catalysts and the asymmetric organic catalysis and their control of chirality are explained,along with the categories of the organic catalysis and the catalysts.The important contributions of Chinese scientists in the field of the organic asymmetric catalysis are introduced,and the development,the research status and the future of this field are highlighted.

关 键 词：2021年诺贝尔化学奖 手性 手性控制 手性有机催化剂 有机不对称催化 

分 类 号：O621.251[理学—有机化学]