新生儿重症监护室医院感染高危因素分析  

Analysis of high risk factors of nosocomial infection in neonatal intensive care unit

作　　者：赵文静[1] 范娟[2] 张先红 王建辉 谢洁 付利珍 ZHAO Wen-jing;FAN Juan;ZHANG Xian-hong;WANG Jian-hui;XIE Jie;FU Li-zhen(Children's Hospital of Chongqing Medical University,Chongqing 400014;Ministry of Education Key Laboratory of Child Development and Disorders;National Clinical Research Center for Child Health and Disorders;China International Science and Technology Cooperation Base of Child Development and Critical Disorders;Chongqing Key Laboratory of Pediatrics,China)

机构地区：[1]重庆医科大学附属儿童医院,重庆400014 [2]儿童发育疾病研究教育部重点实验室 [3]国家儿童健康与疾病临床医学研究中心 [4]儿童发育重大疾病国家国际科技合作基地 [5]儿科学重庆市重点实验室

出　　处：《中国消毒学杂志》2021年第11期824-827,共4页Chinese Journal of Disinfection

基　　金：重庆市科委技术创新与应用示范(社会民生类一般项目)(cstc2018jscx-msybX0071)。

摘　　要：目的调查新生儿重症监护病房(NICU)医院感染发生情况及其高危因素,为有效控制NICU医院感染提供依据。方法采用回顾性调查方法,对某儿童医院NICU住院新生儿医院感染情况及其危险因素进行调查与分析。结果共调查住院新生儿患者9544例,发生医院感染232例、244例次,医院感染率为2.43%、例次感染率2.56%。感染部位居前3位的分别为呼吸道、血液或导管和消化道,感染率构成比依次为48.77%、43.03%和5.33%。早产儿和体重<1500 g、有创性操作、有激素治疗史、住院时间长等构成NICU医院感染的高危因素。结论NICU医院感染以早产儿为主要感染群体,应针对高危因素采取有效防控措施,以降低医院感染率。Objective To investigate the incidence and high-risk factors of nosocomial infections in the neonatal intensive care unit(NICU),and to provide evidence for effective control of nosocomial infections in the NICU.Methods A retrospective investigation method was used to investigate and analyze the nosocomial infection and its risk factors of neonates hospitalized in the NICU of a children's hospital.Results A total of 9544 hospitalized neonatal patients were investigated.There were 232 neonates with nosocomial infection and 244 cases of infection.The incidence of nosocomial infection was 2.43%and the rate of infection cases was 2.56%.The top three sites of infection were the respiratory tract,blood or catheter,and digestive tract.The constituent ratios of the infection rate were 48.77%,43.03%,and 5.33%,respectively.Premature infants and weight<1500 g,invasive procedures,history of hormone therapy,long hospital stay were the high-risk factors for nosocomial infection in NICU.Conclusion Premature infants are the main population of nosocomial infections in NICU.Effective prevention and control measures should be taken for high-risk factors to reduce the rate of nosocomial infections.

关 键 词：新生儿重症监护病房 医院感染 高危因素 

分 类 号：R181.32[医药卫生—流行病学]