排卵期针刺联合中药补肾调周疗法治疗未破裂卵泡黄素化综合征肾虚证临床疗效观察  

Acupuncture combined Bushen Tiaozhou Method treatment the clinical effect for luteinized unruptured follicle syndrome of kidney deficiency during ovulation time

作　　者：张庆[1] 陈冬梅 王全利 张霞 邢玉[3] 万朝霞[1] ZHANG Qing;CHEN Dongmei;WANG Quanli;ZHANG Xia;XING Yu;WAN Zhaoxia(Department of Gynecology,Nantong Hospital Affiliated to Nanjing University of Chinese Medicine,Nantong,Jiangsu 226000;不详)

机构地区：[1]南京中医药大学附属南通医院妇科,江苏南通226000 [2]江苏省南通市如东县中医院妇科,江苏如东226400 [3]北京中医药大学附属东方医院妇科,北京100071

出　　处：《河北中医》2021年第8期1261-1265,1271,共6页Hebei Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(编号:81904241);2013-2014年度江苏省中医药局科技项目(编号:LZ13161);南通市卫生和计划生育委员会青年医学人才科研基金项目(编号:WKZL2018029)。

摘　　要：目的观察排卵期针刺联合中药补肾调周疗法治疗未破裂卵泡黄素化综合征(LUFS)肾虚证的临床疗效。方法将60例LUFS肾虚证患者按照随机数字表法分为3组。西药组20例予西药促排卵治疗,中药组20例予补肾调周中药治疗,针药结合组20例在中药组治疗基础上联合排卵期针刺治疗。3组均连续治疗3个月经周期。统计3组排卵率,比较3组治疗前后中医证候评分、子宫内膜超声评分及子宫内膜血流搏动指数(PI)、阻力指数(RI)。结果针药结合组总排卵率71.67%(43/60),中药组总排卵率51.67%(31/60),西药组总排卵率45.00%(27/60),针药结合组排卵率高于中药组及西药组(P<0.05)。治疗后针药结合组腰骶痠痛、性欲减退、胫痠膝软或足跟痛、耳鸣、月经不调、经色、经质评分及总分均较本组治疗前降低(P<0.05),且均低于西药组治疗后(P<0.05);治疗后中药组腰骶痠痛、性欲减退、胫痠膝软或足跟痛、夜尿频多、月经不调、经质评分及总分均较本组治疗前降低(P<0.05),且均低于西药组治疗后(P<0.05)。治疗后针药结合组、中药组子宫内膜超声评分均较本组治疗前升高(P<0.05),且均高于西药组(P<0.05)。治疗后针药结合组、中药组PI均较本组治疗前降低(P<0.05),且均低于西药组治疗后(P<0.05),针药结合组PI低于中药组(P<0.05);治疗后针药结合组RI降低(P<0.05),且均低于中药组、西药组治疗后(P<0.05)。结论排卵期针刺联合中药补肾调周疗法治疗可促进LUFS肾虚证患者正常排卵,改善临床症状,提高子宫内膜容受性,适合临床推广应用。Objective To observe acupuncture combined Bushen Tiaozhou Method treatment the clinical effect for luteinized unruptured follicle syndrome(LUFS)of kidney deficiency during ovulation time.Methods Totally 60 patients with LUFS(kidney deficiency)were randomly divided into western medicine(WM)group,traditional Chinese medicine(TCM)group and combination group(combination of acupuncture and medicine),20 cases per group.during ovulation time,Patients in WM group were given drug for ovulation induction,patients in TCM group given Bushen Tiaozhou Method,and patients in combination group given acupuncture on the basis of TCM group,additionally.The treatment continued 3 menstrual cycles in two groups,the aim was to compare ovulation rate,TCM syndrome scores,ultrasound score for detection of endometrial,endometrial blood flow parameters such as pulsatile indexes(PI)and resistant index(RI).Results The total ovulation rate was 71.67%(43/60)for combination group,51.67%(31/60)for TCM group,and 45.00%(27/60)for WM group,respectively,the ovulation rate being better in combination group than TCM and WM groups(P<0.05).After treatment,TCM syndrome scores(lumbosacral pain,debility sexualis,tibial weakness,heel pain,Tinnitus or deafness,irregular menstruation,menstrual colour,menstrual property)in combination group were decreased(P<0.05),which decreased notably in combination group when compared with WM group(P<0.05);TCM syndrome scores(lumbosacral pain,debility sexualis,tibial weakness,heel pain,nocturnal polyuria,irregular menstruation,menstrual property)in TCM group remarkably decreased(P<0.05),which was significantly lower in TCM group than in WM group(P<0.05).Compared with before treatment,ultrasound score in combination group and TCM group was higher after treatment(P<0.05),which increased notably when compared with WM group(P<0.05).PI in combination group and TCM group remarkably decreased,WM group was the highest among groups,the order of arrangement from low to high in turn was combination group,TCM group,WM group(all P<0.05).

关 键 词：卵泡 无排卵 肾虚 中药疗法 针刺疗法 

分 类 号：R711.605.31[医药卫生—妇产科学] R245.31[医药卫生—临床医学]