复发性流产与精子畸形率及DFI的相关性分析  

The study of the correlation between the recurrent pregnancy loss and sperm malformation rate and sperm DFI

作　　者：朱元[1] 李欢欢[2] 艾丹[1] 钟丽珍[1] 王长华[1] ZHU Yuan;LI Huanhuan;AI Dan(Department of Reproductive Health,Jiangxi Hospital for Women and Children,Nan Chang,Jiangxi 330006,China;Department of Anesthesiology,Jiangxi Hospital for Women and Children,Nan Chang,Jiangxi 330006,China)

机构地区：[1]江西省妇幼保健院生殖健康科,南昌330006 [2]江西省妇幼保健院麻醉科,南昌330006

出　　处：《江西医药》2021年第10期1592-1594,共3页Jiangxi Medical Journal

基　　金：江西省卫计委科技计划项目,编号20175430。

摘　　要：目的研究精子畸形率及精子DFI与复发性流产的相关性。方法选取2020年1月-2021年1月于我院妇科内分泌门诊就诊有复发性流产史配偶男性患者78例(复发性流产组),有正常生育史配偶男性100例(对照组),将2组的畸形精子百分比率与精子DFI进行比较。结果复发性流产组的精子畸形率(93.7±23.5 Vs 73.8±17.8)和精子DFI(32.3±8.8 Vs 11.6±6.9),相比于对照组来说更高(P<0.05)。结论高精子畸形率及高精子DFI会增加复发性流产的发生风险,通过改善男性精子质量,可降低复发性流产发生的风险。Objective To analyze the correlation between the recurrent pregnancy loss and sperm malformation rate and sperm DFI.Methods 78 men with recurrent spontaneous abortion history of their wives were enrolled in the experimental group from January 2020 to December 2020,and during the same period 100 men whose wives didn’t have a pregnancy loss history were recruited in the control group.For studying the correlation between the sperm DFI and the percentage of morphologically abnormal sperm and the recurrent pregnancy loss,the sperm DFI and the percentage of morphologically abnormal sperm of the recurrent spontaneous abortion group and the control group were compared.Results The difference of the percentage of morphologically abnormal sperm(93.7±23.5 Vs 73.8±17.8)and sperm DFI(32.3±8.8 Vs 11.6±6.9)between the two groups are statistically significant,P<0.05.Conclusion Recurrent pregnancy loss closely correlates with the sperm deformity rate and sperm DFI.Improving sperm quality may reduce the risk of the recurrent spontaneous abortion.

关 键 词：复发性流产 精子畸形率 精子DFI 

分 类 号：R714.21[医药卫生—妇产科学]