地奈德乳膏联合薇诺娜宝贝舒润滋养霜治疗婴幼儿湿疹疗效观察  

Observation on the therapeutic efficacy of desonide cream combined with Winona baby nourishing ultra-rich cream in the treatment of infantile eczema

作　　者：史俊奇[1] 董小双[1] 章岚岚[1] 裴宇[1] SHI Junqi;DONG Xiaoshuang;ZHANG Lanlan;PEI Yu(Department of Pediatrics,the Third People′s Hospital of Hangzhou,Hangzhou 310000,China)

机构地区：[1]杭州市第三人民医院儿科,浙江杭州310000

出　　处：《中国现代医生》2021年第29期1-4,共4页China Modern Doctor

基　　金：浙江省中医药科学研究基金项目(2021ZB227)。

摘　　要：目的探讨婴幼儿湿疹薇诺娜宝贝舒润滋养霜联合地奈德乳膏治疗的疗效。方法回顾性选取2019年6月至2020年6月本院婴幼儿湿疹患儿100例,依据治疗方法分为单独地奈德乳膏治疗组(单独治疗组,n=50)与薇诺娜宝贝舒润滋养霜联合地奈德乳膏治疗组(联合治疗组,n=50)两组,对两组患者的症状体征评分、临床疗效、不良反应发生情况、复发情况进行统计分析。结果联合治疗组患儿治疗后较治疗前的瘙痒程度、皮损情况、皮损范围评分及总分降低幅度均显著高于单独治疗组,差异有统计学意义(P<0.05)。联合治疗组患者治疗的总有效率为92.0%(46/50),显著高于单独治疗组的64.0%(32/50),差异有统计学意义(P<0.05)。联合治疗组不良反应发生率为8.0%(4/50),单独治疗组为6.0%(3/50),两组比较,差异无统计学意义(P>0.05);联合治疗组患者的复发率为6.0%(3/50),显著低于单独治疗组的38.0%(19/50)(P<0.05)。结论婴幼儿湿疹采用薇诺娜宝贝舒润滋养霜联合地奈德乳膏治疗的疗效较单独地奈德乳膏治疗显著。Objective To explore the therapeutic efficacy of Winona baby nourishing ultra-rich cream combined with desonide cream in the treatment of infantile eczema.Methods A total of 100 cases of infantile eczema admitted to our hospital from June 2019 to June 2020 were selected retrospectively,and they were divided into the single group of desonide cream(the single treatment group,n=50)and the treatment group of Winona baby nourishing ultra-rich cream combined with desonide cream(the combined treatment group,n=50).The scores of symptom and sign,clinical efficacy,adverse reactions(ARs)and relapse condition of patients in the two groups were statistically analyzed.Results After treatment,the pruritus degree,skin lesion condition,skin lesion range score and total score of children in the combined treatment group were all significantly higher than those in the single treatment group(P<0.05).The total effective rate of patients in the combined treatment group was 92.0%(46/50),which was significantly higher than 64.0%(32/50)in the single treatment group(P<0.05).The incidence of ARs was 8.0%(4/50)in the combined treatment group and 6.0%(3/50)in the single treatment group,without significant difference between the two groups(P>0.05).The relapse rate of patients in the combined treatment group was 6.0%(3/50),which was significantly lower than 38.0%(19/50)in the single treatment group(P<0.05).Conclusion The efficacy of Winona baby nourishing ultra-rich cream combined with desonide cream in the treatment of infantile eczema is more remarkable than that of desonide cream alone.

关 键 词：婴幼儿湿疹 薇诺娜宝贝舒润滋养霜 地奈德乳膏 症状体征评分 不良反应 复发 

分 类 号：R758.2[医药卫生—皮肤病学与性病学]