Diagnosis,fetal risk and treatment of pemphigoid gestationis in pregnancy:A case report  

作　　者：Hai-Ning Jiao Ye-Ping Ruan Yan Liu Meng Pan Hui-Ping Zhong 

机构地区：[1]Department of Obstetrics and Gynecology,Rui-Jin Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China [2]Department of Dermatology,Rui-Jin Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China

出　　处：《World Journal of Clinical Cases》2021年第34期10645-10651,共7页世界临床病例杂志

摘　　要：BACKGROUND Pemphigoid gestationis(PG)is a rare autoimmune blistering disease that usually presents in the second or third trimester,with an incidence of 1 per 50000 pregnancies.PG tends to recur with an earlier onset and a more severe course in subsequent pregnancies.Skin biopsy markers can be confirmed by direct immunofluorescence staining.CASE SUMMARY Our patient was diagnosed with PG at 8 mo of gestation with fresh bullous lesion marks on the abdomen and limbs.Termination of the pregnancy was performed by cesarean section at 37+4 wk of gestation.The patient delivered an infant weighing 3620 gm.The infant had urticaria-like and vesicular skin lesions and was diagnosed with PG.The patient was discharged on prednisolone and in a satisfactory condition.The infant was discharged after anti-inflammatory therapy for one week.CONCLUSION PG is a rarely reported disease,and 10%of newborns develop mild clinical symptoms consisting of urticaria-like or vesicular skin lesions.We intend to remind clinicians to consider this condition when a patient presents with such lesions so that treatment can be started early and neonatal morbidity can be taken into account.

关 键 词：Pemphigoid gestationis PREGNANCY NEWBORN PEMPHIGUS Fluorescent antibody techniqu Case report 

分 类 号：R714.259[医药卫生—妇产科学]