孕早期营养干预对妊娠期糖尿病高危妇女糖脂代谢及胎儿预后的影响效果观察  

Effect of Nutritional Intervention in Early Pregnancy on Glucose and Lipid Metabolism and Fetal Prognosis in High-risk Women with Gestational Diabetes

作　　者：梅苏珍 MEI Suzhen(Department of Obstetrics,Second Hospital of Sanming City,Sanming,Fujian Province,366000 China)

机构地区：[1]福建省三明市第二医院产科,福建三明366000

出　　处：《糖尿病新世界》2021年第20期64-67,共4页Diabetes New World Magazine

摘　　要：目的观察孕早期营养干预对妊娠期糖尿病高危妇女糖脂代谢及胎儿预后的影响效果。方法选取2019年2月-2020年10月该院收治的82例妊娠期糖尿病高危妇女为研究对象,随机分为两组,对照组(41例)妊娠期糖尿病高危妇女应用常规治疗方式,研究组(41例)妊娠期糖尿病高危妇女在对照组治疗的基础上应用孕早期营养干预,观察和比较两组新生儿结局、孕妇妊娠结局、孕妇生活质量及干预前后糖脂代谢水平。结果对比两组干预前糖脂代谢水平差异无统计学意义(P>0.05);对比干预后数据,两组TC对比差异无统计学意义(P>0.05)。研究组HbAlc(5.02±0.41)%、FPG(4.50±0.32)mmol/L、TG(2.13±0.60)mmol/L、2 hPG(6.68±0.73)mmol/L均低于对照组,差异有统计学意义(P<0.05)。研究组剖宫产率(14.63%)、GDM(12.20%)、GWG(10.36±3.02)kg均低于对照组,差异有统计学意义(P<0.05),但两组产后出血率、PHD相比差异无统计学意义(P>0.05)。研究组的新生儿体质量(3568.57±30.84)g、巨大儿发生率(2.44%)均低于对照组,差异有统计学意义(P<0.05),但两组新生儿低血糖发生率、窒息发生率相比差异无统计学意义(P>0.05)。研究组的生理职能评分(60.84±33.25)分、情感职能评分(77.42±31.24)分、心理健康评分(79.87±9.21)分、社会功能评分(97.88±12.58)分均高于对照组,差异有统计学意义(P<0.05)。结论将孕早期营养干预应用在妊娠期糖尿病高危妇女的治疗中对改善其糖脂代谢水平、降低GDM发生率、剖宫产率有较大的促进作用,有利于改善孕妇的生活质量、妊娠结局及提高胎儿预后效果,临床应用价值较高。Objective To observe the effect of nutritional intervention in early pregnancy on glucose and lipid metabolism and fetal prognosis in high-risk women with gestational diabetes.Methods From February 2019 to October 2020,82 high-risk women with gestational diabetes mellitus were selected as the subjects,and randomly divide them into two groups.The control group(41 cases)women at high risk of gestational diabetes were treated with conventional treatment,and the study group(41 cases)women at high risk of gestational diabetes were treated with early pregnancy nutrition intervention based on the treatment of the control group.Observed and compared the two groups of neonatal outcomes,pregnancy outcomes of pregnant women,maternal quality of life,and glucose and lipid metabolism levels before and after intervention.Results There was no significant difference in glucose and lipid metabolism between the two groups before intervention(P>0.05).There was no significant difference in TC between the two groups(P>0.05).After inter vention,HbAlc(5.02±0.41)%,FPG(4.50±0.32)mmol/L,TG(2.13±0.60)mmol/L and 2 hPG(6.68±0.73)mmol/L in the study group were significantly lower than those in the control group,and the difference was statistically significant(P<0.05).The cesarean section rate(14.63%),GDM(12.20%)and GWG(10.36±3.02)kg in the study group were significantly lower than those in the control group,and the difference was statistically significant(P<0.05),but there was no significant difference in postpartum hemorrhage rate and PHD between the two groups(P>0.05).The neonatal body mass(3568.57±30.84)g and the incidence of macrosomia(2.44%)in the study group were significantly lower than those in the control group,and the difference was statistically significant(P<0.05),but there was no significant difference in the incidence of neonatal hypoglycemia and asphyxia between the two groups(P>0.05).The scores of physiological function(60.84±33.25)points,emotional function(77.42±31.24)points,mental health(79.87±9.21)points and social

关 键 词：妊娠期糖尿病 孕早期营养干预 高危 糖脂代谢 

分 类 号：R587[医药卫生—内分泌]