新生儿呼吸窘迫综合征联合应用PAV与SIMV的疗效分析  

Analysis of the Curative Effect of Combined Application of PAV and SIMV in Neonatal Respiratory Distress Syndrome

作　　者：任素敏 REN Sumin(The First People's Hospital of Ningyang County,Tai'an,Shandong Province,271400 China)

机构地区：[1]山东省泰安市宁阳县第一人民医院,山东泰安271400

出　　处：《系统医学》2021年第19期120-122,共3页Systems Medicine

摘　　要：目的观察新生儿呼吸窘迫综合征(RDS)联合应用比例辅助通气(PAV)与同步间歇指令通气(SIMV)的疗效。方法研究病例为2019年3月-2020年3月该院收治的74例RDS患儿,依据住院日期以及床位号的奇偶性划分为对照组(SIMV模式通气治疗)、研究组(PAV+SIMV模式通气治疗)各包含37例患儿;对比两组患儿治疗前后的血气指标以及不同时间平均气道压(MAP)、人机对抗次数、低碳酸血症发生率。结果治疗后研究组患儿的PaCO_(2)指标(43.15±5.44)mmHg低于对照组,组间差异有统计学意义(t=4.843,P<0.05);治疗1、6、12、24、48 h研究组患儿的MAP指标(12.05±0.76)、(11.92±0.55)、(11.75±0.62)、(11.56±0.56)、(10.24±0.76)cmH_(2)O与人机对抗次数(22.02±6.08)、(21.05±6.65)、(19.12±6.96)、(17.76±6.32)、(16.05±5.95)次均低于对照组,差异有统计学意义(t=5.772、7.903、6.186、3.802、3.863、5.578、5.061、5.613、4.945、3.663,P<0.05);研究组中低碳酸血症占比为2.70%,低于对照组的21.62%,组间差异有统计学意义(χ^(2)=4.554,P<0.05)。结论RDS患儿联合给予PAV+SIMV模式通气治疗,人机同步性能良好,氧合指数相等的情况下,可以改善PaCO_(2)水平以及MAP,降低低碳酸血症风险。Objective To observe the effect of neonatal respiratory distress syndrome(RDS)combined with proportional assisted ventilation(PAV)and synchronized intermittent mandatory ventilation(SIMV).Methods The study cases were 74 children with RDS admitted to the hospital from March 2019 to March 2020.According to the date of hospitalization and the parity of the bed number,they were divided into the control group(SIMV mode ventilation treatment)and the test group(PAV+SIMV mode ventilation therapy)each included 37 children;the blood gas indexes before and after treatment,mean airway pressure(MAP)at different times,the number of man-machine confrontations,and the incidence of hypocapnia were compared between the two groups of children.Results After treatment,the PaCO_(2) index(43.15±5.44)mmHg of the children in the study group was lower than that of the control group,the difference was statistically significant(t=4.843,P<0.05);the study group was treated for 1 h,6 h,12 h,24 h,48 h of the child’s MAP index(12.05±0.76)cmH_(2)O,(11.92±0.55)cmH_(2)O,(11.75±0.62)cmH2O,(11.56±0.56)cmH2O,(10.24±0.76)cmH_(2)O and man-machine confrontation times(22.02±6.08)times,(21.05±6.65)times,(19.12±6.96)times,(17.76±6.32)times,(16.05±5.95)times were lower than the control group,the difference was statistically significant(t=5.772,7.903,6.186,3.802,3.863,5.578,5.061,5.613,4.945,3.663,P<0.05);hypocapnia proportion of symptoms in the study group was 2.70%,which was lower than 21.62%in the control group.There was a statistically significant difference between the groups(χ^(2)=4.554,P<0.05).Conclusion Children with RDS are given combined PAV+SIMV ventilation therapy,the man-machine synchronization performance is good,and when the oxygenation index is equal,it can improve the PaCO_(2) level and MAP,and reduce the risk of hypocapnia.

关 键 词：新生儿呼吸窘迫综合征 PAV SIMV 血气指标 MAP 低碳酸血症 

分 类 号：R246.4[医药卫生—针灸推拿学]