金糖宁胶囊联合卡格列净治疗2型糖尿病的临床价值  

Clinical Value of Jintangning Capsule Combined with Canagliflozin in the Treatment of Type 2 Diabetes

作　　者：蒲先锋 PU Xianfeng(Chinese Pharmacy,Shandong Guoxin Yiyang Group Zibo Hospital,Zibo,Shandong Province,255120 China)

机构地区：[1]山东国欣颐养集团淄博医院中药房,山东淄博255120

出　　处：《糖尿病新世界》2021年第19期106-109,共4页Diabetes New World Magazine

摘　　要：目的探析金糖宁胶囊联合卡格列净治疗2型糖尿病的临床效果。方法该文选取2019年5月—2020年5月收治的120例2型糖尿病患者进行分析,根据随机数表法分为对照组与观察组,各60例。对照组给予卡格列净治疗,观察组给予卡格列净+金唐宁胶囊治疗,观察两组血糖指标、总有效率、不良反应发生率、动态血糖监测。结果治疗后,观察组空腹血糖(FPG)、餐后2 h血糖(2 hPG)、糖化血红蛋白(HbA1c)等指标低于对照组,差异有统计学意义(P<0.05);观察组糖尿病酮症、呕吐、尿路感染发生率较对照组低,差异有统计学意义(P<0.05);观察组MAGE、MBC、SDBG低于对照组,差异有统计学意义(P<0.05);观察组治疗总有效率为96.67%,高于对照组的83.33%,差异有统计学意义(P<0.05)。结论金糖宁胶囊联合卡格列净治疗对降低2型糖尿病患者血糖效果显著,胰岛素抗体水平改善明显,提高临床症状,减少不良反应,临床应用效果显著。Objective To explore the clinical effect of Jintangning capsule combined with canagliflozin in the treatment of type 2 diabetes.Methods This article selected 120 patients with type 2 diabetes admitted from May 2019 to May 2020 for analysis,and divided them into a control group and an observation group according to the random number table method,with 60 cases in each group.The control group was treated with canagliflozin.The observation group was treated with canagliflozin +Jintangning Capsule,and the blood glucose index,total effective rate,incidence of adverse reactions,and dynamic blood glucose monitoring were observed in the two groups.Results After treatment,the observation group’s fasting blood glucose(FPG),postprandial blood glucose(2 hPG),glycosylated hemoglobin(HbA1 c) and other indicators were lower than those of the control group,and the difference was statistically significant(P<0.05).The incidence of diabetic ketosis,vomiting,and urinary tract infection in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).The MAGE,MBC and SDBG of the observation group were lower than those of the control group,the difference was statistically significant(P<0.05).The total effective rate of treatment in the observation group was 96.67%,which was higher than 83.33% in the control group,and the difference was statistically significant(P<0.05).Conclusion Jintangning capsule combined with canagliflozin treatment has a significant effect on reducing blood glucose in patients with type 2 diabetes,significantly improving insulin antibody levels,improving clinical symptoms,reducing adverse reactions,and having significant clinical application effects.

关 键 词：金糖宁胶囊 卡格列净 2型糖尿病 

分 类 号：R587.1[医药卫生—内分泌]