鱼腥草(Houttuynia cordata)提取物对结肠癌细胞HCT116增殖的抑制作用  

Inhibitory Effect of Houttuynia cordata Extract on Proliferationof Colon Cancer Cell HCT116

作　　者：尚姝明 张晓军[1] 马天宇 张昊 于凤超[1] 齐宏玥 陈泳泽 庄松霖 王尚鹏 SHANG Shuming;ZHANG Xiaojun;MA Tianyu;ZHANG Hao;YU Fengchao;QI Hongyue;CHEN Yongze;ZHUANG Songlin;WANG Shangpeng(Mudanjiang Nomal University Life Science and Technology College,Mudanjiang 157011,China)

机构地区：[1]牡丹江师范学院生命科学与技术学院,黑龙江牡丹江157011

出　　处：《牡丹江师范学院学报（自然科学版）》2021年第4期36-39,共4页Journal of Mudanjiang Normal University：Natural Sciences Edition

基　　金：2020年黑龙江省高等教育教学改革研究项目(SJGY20200739);牡丹江师范学院研究生科技创新项目(kjcx2020-11mdjnu,kjcx2020-68mdjnu,kjcx2020-76mdjnu);牡丹江师范学院大学生创新创业训练计划项目(202010233090)。

摘　　要：运用细胞生存活力测定实验(MTT)研究鱼腥草提取物对人结肠癌细胞HCT116生长的抑制情况.采用倒置显微镜观察不同浓度鱼腥草提取物对结肠癌细胞HCT116形态的影响.实验结果表明,鱼腥草提取物对人结肠癌细胞HCT116的生长增殖有明显的抑制作用,且存在浓度和时间的依赖性.鱼腥草作为天然抗肿瘤化合物的筛选材料具有潜在的价值.Cell viability assay(MTT)was used to study the growth inhibition of Houttuynia cordata Thunb.extract on human colon cancer cell HCT116.The effect of Houttuynia cordata extract at different concentrations on the morphology of HCT116 colon cancer cells was observed by inverted microscope.The results showed that Houttuynia cordata extract had significant inhibitory effect on the growth and proliferation of human colon cancer cell HCT116 in a concentration and time dependent manner.Houttuynia cordata has potential value as a screening material for natural anti-tumor compounds.

关 键 词：鱼腥草 结肠癌细胞 MTT 

分 类 号：Q291[生物学—细胞生物学]