丙泊酚联合七氟烷对减少小儿麻醉苏醒期躁动的效果和安全性观察  

Observation on the effect and safety of propofol combined with sevoflurane on reducing restlessness during awakening from anesthesia in children

作　　者：李强[1] LI Qiang(Department of Anesthesiology,Linyi Traditional Chinese Medical Hospital,Linyi,Shandong,276000,China)

机构地区：[1]山东省临沂市中医医院麻醉科,山东临沂276000

出　　处：《当代医学》2021年第35期31-33,共3页Contemporary Medicine

摘　　要：目的探究丙泊酚联合七氟烷麻醉对小儿麻醉苏醒期躁动的效果。方法选取2018年1月至2020年3月于本院接受手术治疗的300例小儿患者作为研究对象,根据麻醉药物不同分为对照组(七氟烷常规麻醉,n=147)和观察组(丙泊酚联合七氟烷麻醉,n=153)。比较两组麻醉效果、心率及血氧饱和度水平、麻醉苏醒期躁动评分及麻醉安全性。结果观察组麻醉起效时间、自主呼吸恢复时间、拔管时间、睁眼时间及清醒时间均短于对照组,差异有统计学意义(P<0.05)。T1、T2、T3时,观察组心率、血氧饱和度水平较稳定,与对照组比较差异有统计学意义(P<0.05)。苏醒时、拔管时、拔管30 min,观察组麻醉苏醒期躁动评分均低于对照组,差异有统计学意义(P<0.05)。观察组不良反应发生率为3.9%,明显低于对照组的12.9%,差异有统计学意义(P<0.05)。结论对接受手术治疗的小儿患者实施丙泊酚联合七氟烷麻醉效果显著,可有效减少患儿麻醉苏醒期躁动,具有较高的麻醉安全性。Objective To explore the effect of propofol combined with sevoflurane anesthesia on emergence agitation in children.Methods 300 pediatric patients who underwent surgical treatment in our hospital from January 2018 to March 2020 were selected as the research subjects.According to the different anesthetic drugs,they were divided into control group(sevoflurane conventional anesthesia,n=147)and observation group(propofol combined with sevoflurane anesthesia,n=153).The anesthesia effect,heart rate and blood oxygen saturation level,agitation score during anesthesia recovery and the safety of anesthesia between the two groups were compared.Results The onset time of anesthesia,spontaneous breathing recovery time,extubation time,eye opening time and awake time in the observation group were shorter than those in the control group,the difference was statistically significant(P<0.05).At T1,T2,and T3,the heart rate and oxygen saturation in the observation group were stable,and the difference was statistically significant(P<0.05).At awakening,extubation,and 30 minutes after extubation,the agitation scores of the observation group during anesthesia recovery were lower than those of the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group was 3.9%,which was significantly lower than 12.9%in the control group,the difference was statistically significant(P<0.05).Conclusion The anesthesia effect of propofol combined with sevoflurane for pediatric patients receiving surgical treatment is significant,which can effectively reduce the restlessness during anesthesia recovery period and has high anesthesia safety.

关 键 词：丙泊酚 七氟烷 麻醉苏醒期躁动 麻醉效果 安全性 

分 类 号：R726.1[医药卫生—儿科]