星刺卫矛的化学成分研究  

Chemical constituents of Euonymus actinocarpus

作　　者：刘淑萍 季泓源 张建英 张慧颖 李亶烨 左爱学 LIU Shuping;JI Hongyuan;ZHANG Jianying;ZHANG Huiying;LI Danye;ZUO Aixue(College of Traditional Chinese Medicine,Yunnan University of Chinese Medicine,Kunming 650500,China;Basic Medical School,Yunnan University of Chinese Medicine,Kunming 650500,China;Department of Pharmacy,Qujing Medical College,Qujing 655000,Yunnan,China)

机构地区：[1]云南中医药大学中药学院,昆明650500 [2]云南中医药大学基础医学院,昆明650500 [3]曲靖医学高等专科学校药学系,云南曲靖655000

出　　处：《广西植物》2021年第11期1868-1874,共7页Guihaia

基　　金：云南省科技厅科技计划项目(2018FB146)。

摘　　要：为探究卫矛科卫矛属植物星刺卫矛(Euonymus actinocarpus)的化学成分,该文采用正相硅胶、Sephadex LH-20和半制备液相HPLC等色谱技术对其进行分离和纯化。结果表明:(1)从星刺卫矛地上部分95%乙醇提取物中分离得到10个化合物,根据其理化常数和波谱(ESI-MS、1 H-NMR、13 C-NMR)数据鉴定化合物结构为羽扇豆醇(1),蒲公英萜醇(2),表木栓醇(3),槐二醇(4),蒲公英萜酮(5),高粱醇(6),羽扇豆醇乙酸酯(7),木栓酮(8),β-谷甾醇(9),胡萝卜苷(10)。(2)所有化合物均为首次从星刺卫矛中分离得到。(3)星刺卫矛地上部分主要含有三萜和甾体类成分,其中三萜类型以木栓烷型、齐墩果烷型和羽扇豆烷型骨架为主。该研究结果增加了对星刺卫矛物质基础的认识,为开发和利用卫矛属植物资源提供了一定的科学依据。To investigate the chemical constituents of Euonymus actinocarpus in genus Euonymus of family Celastraceae,column chromatography on silica gel,Sephadex LH-20 and semi-preparative liquid chromatography were applied for the isolation and purification of the constituents.The structures were elucidated on the basis of spectral analysis and by comparison the data in literature.The results were as follows:(1)Ten compounds were isolated from the 95%EtOH extract of aerial part of E.actinocarpus,and their structures were identified as lupeol(1),taraxerol(2),epifriedelinol(3),sophoradiol(4),taraxerone(5),sorghumol(6),lupeol acetate(7),friedelin(8),β-sitosterol(9),daucosterol(10),respectively.(2)All isolated compounds 1-10 were reported from E.actinocarpus for the first time.(3)The aerial part of E.actinocarpus mainly contained triterpenoids and steroids,furthermore,the triterpenoids mainly involved pedunane,oleanane and lupanane type skeletons.The results increase the understanding of the material basis of E.actinocarpus,and provide a certain scientific basis for the development and utilization of Euonymus plant resources.

关 键 词：卫矛属 星刺卫矛 化学成分 三萜 

分 类 号：Q946[生物学—植物学]