百色市暗娼队列艾滋病新发感染状况及影响因素研究  

Study on new HIV infection status and influencing factors among female sex workers in Baise

作　　者：廖建英 陈坚[2] 梁旭 谭兰芬[2] LIAO Jianying;CHEN Jian;LIANG Xu;TAN Lanfen(School of Public Health and Management,Youjiang Medical University for Nationalities,Baise 533000,Guangxi,China;Department of AIDS,Baise Center for Disease Control and Prevention,Baise 533000,Guangxi,China)

机构地区：[1]右江民族医学院公共卫生与管理学院,广西百色533000 [2]百色市疾病预防控制中心艾滋病防制科,广西百色533000

出　　处：《右江医学》2021年第11期809-814,共6页Chinese Youjiang Medical Journal

基　　金：百色市科学研究与技术开发计划项目(百科20184201)。

摘　　要：目的了解百色市暗娼(female sex workers,FSWs)人群的艾滋病新发感染情况,并探索该人群中影响艾滋病新发感染的因素,为百色市暗娼的艾滋病防控工作提供科学依据。方法从2016年起对百色市暗娼人群开展持续3年的队列研究,每年随访一次获取其行为学的情况,并进行血清学检测,分析包括入组后有过≥1次随访的基线HIV血清检测为阴性的暗娼,计算该人群HIV的新发感染密度,并建立HIV新发感染影响因素的logistic回归模型。结果纳入队列研究人群共703人,随访保持率为35.8%。队列人群以中年已婚、文化程度低的壮族女性为主,多数是在中低档服务场所,广泛接受过艾滋病干预服务。累计队列人群HIV的观察总人年数为1238.72人年,估计新发感染密度为1.13/100人年(95%CI:0.62~1.79/100人年)。最近一个月安全套的使用频率与暗娼人群的HIV感染有关,非每次使用者感染HIV的风险是每次使用者的17.172倍(95%CI:3.055~96.526)。结论百色市暗娼人群的HIV新发感染率高于一般社区人群,要继续加强暗娼防控工作,构建形成全方位立体化的安全套使用推广体系,以阻断暗娼这个桥梁人群向一般人群传播HIV的危险。Objective To investigate the new HIV infection situation among female sex workers(FSWs)in Baise and explore the factors affecting the new HIV infection among the population,so as to provide scientific evidence for the prevention and control of AIDS in Baise.Methods A three-year cohort study was carried out on female sex workers in Baise City from 2016.They were followed up once a year to obtain the statement of their behaviors,and serological tests were carried out.The female sex workers with negative baseline HIV serum test who had been followed up for≥1 time after enrollment were analyzed,the incidence density of new HIV infection in this population was calculated,and the logistic regression model of influencing factors of new HIV infection was established.Results A total of 703 people were included in the cohort study,and the follow-up retention rate was 35.8%.The cohort was mainly middle-aged,married and poorly educated Zhuang women,most of whom were in medium and low-grade service places,and had widely accepted AIDS intervention services.The total observed person years of HIV in the cumulative cohort population was 1238.72 person years,and the estimated incidence density of new infections was 1.13/100 person years(95%CI:0.62-1.79/100 person years).The frequency of condom use in the last month was related to HIV infection among female sex workers,and the risk of HIV infection among non users was 17.172 times higher than that of each user(95%CI:3.055-96.526).Conclusion The new HIV infection rate of FSWs in Baise city is higher than that of general community population.The prevention and control of FSWs should be continued to strengthen to build a comprehensive and three-dimensional condom use promotion system,so as to block the risk of HIV transmission from FSWs to general population.

关 键 词：暗娼 HIV 队列研究 新发感染 影响因素 

分 类 号：R512.91[医药卫生—内科学]