宿迁市新发现艾滋病感染者和患者首次CD4^(+)T淋巴细胞检测结果分析  

Analysis of the first CD4^(+) T lymphocyte test results from AIDS infectors/patients newlyidentified in Suqian City

作　　者：陈尚林[1] 胡海洋[2] 葛莉[1] 吴海鸥 李娜[1] 郭莹 CHEN Shang-lin;HU Hai-yang;GE Li;WU Hai-ou;LI Na;GUO Ying(Suqian City Center for Disease Control and Prevention,Jiangsu 223800,China;不详)

机构地区：[1]宿迁市疾病预防控制中心,江苏223800 [2]江苏省疾病预防控制中心

出　　处：《医学动物防制》2021年第11期1074-1077,共4页Journal of Medical Pest Control

基　　金：江苏省卫生健康委科研课题—基于限制性抗原亲和力方法的江苏省男男性行为人群HIV新发感染研究(Z2018039)。

摘　　要：目的分析宿迁市新发现艾滋感染者首次CD4;T淋巴细胞结果,为制定防治措施提供科学依据。方法对宿迁市新报告的342例艾滋病感染者进行CD4;T淋巴细胞计数检测,采用IBM SPSS 21对数据进行统计分析。结果 342例感染者中,男性占79.24%,明显多于女性。首次CD4;T淋巴细胞计数个体差异较大,最小值为1个/μl、最大值为1 597个/μl,均值为(439.47±265.05)个/μl,不同年龄、不同婚姻状况、不同文化程度感染者首次CD4;T淋巴细胞检测结果差异均有统计学意义(F=8.609、4.729、2.746,P<0.05),不同性别感染者首次CD4^(+)/CD8^(+)比值差异有统计学意义(F=5.032,P<0.05)。结论宿迁市存在部分晚发现AIDS患者。建议面向基层农村、女性和已婚有配偶者加强艾滋病知识宣传,同时进一步扩大检测范围、加大检测力度,及早发现感染者,及时提供CD4^(+)T淋巴细胞检测,尽快进行抗病毒治疗,提高患者生存质量。Objective To analyze the first CD4^(+)T lymphocyte results of AIDS patients newly identified in Suqian City and to provide a scientific basis for the development of prevention and control measures.Methods The CD4^(+)T lymphocyte count test was conducted on 342 cases of AIDS infectors newly reported in Suqian City, and the data were statistically analyzed using IBM SPSS 21.Results Among 342 infected cases, 79.24% were men, significantly more than women.The first CD4^(+)T lymphocyte count varied greatly among individuals, with the minimum as 1/μl and the maximum as 1 579/μl.The average value is(439.47±265.05)/μl.The differences in first CD4^(+)T lymphocyte test results were statistically significant by age, marital status, and education level of infection(F=8.609,4.729,2.746,P<0.05),and the differences in the first CD4^(+)/CD8^(+) ratio were statistically significant by gender of infected people(F=5.032,P<0.05).Conclusion Some AIDS patients are identified in later stages in Suqian City.It is suggested that knowledge propaganda should be strengthened for grassroots rural areas, women and married couples.Meanwhile, test scope and strengths should be enlarged to identify infectors at early stages for timely CD4^(+)T lymphocyte test and antivirus treatment as soon as possible to improve the survival quality of patients.

关 键 词：艾滋病 CD4^(+)T淋巴细胞 检测 感染 免疫功能 

分 类 号：R512.91[医药卫生—内科学]