黄花角蒿的历史沿革、化学成分及药理活性研究进展  

Research progress on historical evolution,chemical constituents and pharmacological activities of Incarvillea sinensis var.przewalskii

作　　者：李硕[1,2,3] 李响 杨康 杨秀娟 王智勇[4] 施小宁 李越峰 LI Shuo;LI Xiang;YANG Kang;YANG Xiu-juan;WANG Zhi-yong;SHI Xiao-ning;LI Yue-feng(Gansu University of Traditional Chinese Medicine,Lanzhou 730000,China;Key Laboratory of Chemistry and Quality for Traditional Chinese Medicines of the College of Gansu Province,Lanzhou 730000,China;Key Laboratory of Traditional Chinese Medicine Quality and Standard,Lanzhou 730000,China;Gansu Province Traditional Chinese Medicine Modern Pharmaceutical Engineering Research Institute,Lanzhou,730000,China)

机构地区：[1]甘肃中医药大学,甘肃兰州730000 [2]甘肃省高校中(藏)药化学与质量研究省级重点实验室,甘肃兰州730000 [3]甘肃省中药质量与标准研究重点实验室培育基地,甘肃兰州730000 [4]甘肃省中药现代制药工程研究院有限公司,甘肃兰州730000

出　　处：《中草药》2021年第22期7066-7071,共6页Chinese Traditional and Herbal Drugs

基　　金：国家自然科学基金资助项目(81960713);甘肃省中医药管理局项目(GZK-2017-7,2018ZD04);甘肃省自然科学基金项目(18JR3RA201);甘肃省高校中(藏)药化学与质量研究省级重点实验室项目(zzy-2018-06);甘肃省高等学校创新基金项目(2021A-079);敦煌医学与转化教育部重点实验室2020年度开放课题(DHYX20-10);甘肃省高等学校创新项目(2019A-077)。

摘　　要：黄花角蒿Incarvillea sinensis var.przewalskii为紫葳科(Bignoniaceae)角蒿属多年生草本植物,主产于甘肃、陕西、青海、四川等地,民间多用其治疗咽炎及口疮,疗效显著,基于黄花角蒿中的化学成分推测,其还具有镇痛、抗炎、抗损伤、抗癌、抗氧化等作用。自古代本草记载以来,黄花角蒿多被记载为角蒿Incarvillea sinensis,与角蒿植株记载混乱,故而对黄花角蒿进行本草考证,对其历史沿革、化学成分及药理作用进行总结与归纳,为研究黄花角蒿进一步研究奠定理论基础。Incarvillea sinensis var.przewalskii(Batalin)C.Y.Wu et W.C.Yi is a perennial herb of the genus Incarvillea in The family Bignoniaceae,mainly produced in Gansu,Qinghai,Sichuan and other places,it is widely used in the folk treatment of pharyngitis and aphthous ulcer,with remarkable curative effect,It is speculated that it also has analgesic effect,anti-inflammatory,anti-cancer,anti-oxidation and other effects.Since the ancient herb records,Incarvillea sinensis var.przewalskii has been mostly recorded as I.sinensis Lam.In this paper,the historical development,chemical components and their pharmacological effects were inferred according to the effects of chemical constituents of Incarvillea sinensis Lam.var.przewalskii and the active components and pharmacological activities of the medicine were predic summarized,laying a certain theoretical foundation for the study of clinical application value of this medicine.

关 键 词：黄花角蒿 历史沿革 化学成分 镇痛 抗炎 抗损伤 抗癌 抗氧化 

分 类 号：R286.2[医药卫生—中药学]