高分辨率测压在胃食管反流病的食道运动功能中应用分析  

Application of high resolution manometry in esophageal motor function of gastroesophageal reflux disease

作　　者：姚晓茹 年媛媛 曹佳馨 YAO Xiaoru;NIAN Yuanyuan;CAO Jiaxin(Baotou Medical College,Baotou 014010,China;Department of Gastroenterology,the Second Affiliated Hospital of Baotou Medical College)

机构地区：[1]包头医学院,内蒙古包头014010 [2]包头医学院第二附属医院消化内科

出　　处：《包头医学院学报》2021年第10期85-89,共5页Journal of Baotou Medical College

摘　　要：目的:探讨高分辨率测压在诊断胃食管反流病中作用。方法:根据高分辨率测压结果,将在我院行高分辨率测压检查的患者分为生理性胃食管反流组和病理性胃食管反流组;根据分组将收集的数据进行分析,比较两组数据的差异性。结果:本研究共纳入80例患者数据。生理性胃食管反流组女性较多,中青年较多(P<0.05);病理性胃食管反流组男性较多,中老年人较多(P<0.05)。数据统计:远端收缩积分(DCI)平均值、最高值具有统计学差异(P<0.05);收缩前沿速度(CFV)、食团内部压力(IBP)、IBP平均最大值均没有统计学意义(P>0.05);食管下括约肌(LES)长度、LES静息压(呼吸平均值)、LES残余压(平均值)、食管上括约肌(UES)静息压、UES残余压、UES松弛持续时间等也均不具有统计学意义(P>0.05),但LES腹段长度及LES-CD分离度具有统计学意义(P<0.05)。结论:病理性胃食管反流患者的食管运动功能比生理性胃食管反流患者的食管运动功能低,食管运动功能障碍是导致病理性胃食管反流病的主要因素。高分辨率测压在诊断胃食管反流病中的具有重要作用,临床医生也可以尝试从解决食管运动功能障的方面进行治疗胃食管反流病。Objective:To explore the role of high-resolution manometry in the diagnosis of gastroesophageal reflux disease.Methods:according to the results of high-resolution manometry,the patients who underwent high-resolution manometry in our hospital were divided into physiological gastroesophageal reflux group and pathological gastroesophageal reflux group;Analyze the collected data according to the grouping,and compare the differences between the two groups of data.Results:a total of 80 patients were included in this study.Physiological gastroesophageal reflux group:the age ranged from 22 to 59 years,and the male to female ratio was 9:11;Pathological gastroesophageal reflux group:the age was 23~78 years old,and the male to female ratio was 13:7.Data statistics:the mean and maximum value of distal systolic integral(DCI)were statistically different(P<0.05);There was no significant difference in systolic front velocity(CFV),internal pressure of food mass(IBP)and internal pressure of food mass(IBP)(mean maximum)(P>0.05);Lower esophageal sphincter(LES)length,Les resting pressure(respiratory mean),Les residual pressure(mean),upper esophageal sphincter(UES)resting pressure,ues residual pressure and ues relaxation duration were also not statistically significant(P>0.05),but Les abdominal length and les-cd separation were statistically significant(P<0.05).Conclusion:the esophageal motor function of patients with pathological gastroesophageal reflux is lower than that of patients with physiological gastroesophageal reflux.Esophageal motor dysfunction is the main factor leading to pathological gastroesophageal reflux disease.It reflects the important role of high-resolution manometry in the diagnosis of gastroesophageal reflux disease.Clinicians can also try to treat gastroesophageal reflux disease from the aspect of solving esophageal motor dysfunction.

关 键 词：高分辨率测压 胃食管反流病 食管运动功能 

分 类 号：R73[医药卫生—肿瘤]