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作 者:郭威[1] 杨凡[1] 孙斯琴 王潇 GUO Wei;YANG Fan;SUN Siqin;WANG Xiao(Department of Radiology,Wuhan Third Hospital,Tongren Hospital of Wuhan University,Wuhan Hubei 430063,China;Department of Emergency,General Hospital of Central Theater Command of PLA,Wuhan Hubei 430070,China)
机构地区:[1]武汉市第三医院(武汉大学附属同仁医院)放射科,湖北武汉430063 [2]中国人民解放军中部战区总医院急诊科,湖北武汉430070
出 处:《中国医疗设备》2021年第12期85-89,共5页China Medical Devices
基 金:武汉市卫生健康科研基金资助项目(WX19Y05)。
摘 要:目的探讨磁共振常规联合多b值磁共振扩散加权成像(Diffusion Weighted Imaging,DWI)序列对家兔肢体高压电击伤的诊断价值。方法30只清洁级大白兔随机分为病例组(16只)与影像组(14只),于高压电击后2、24、48、72 h分别处死1只病例组家兔,作病理切片及HE染色;通过MRI平扫联合多b值DWI及增强扫描,对高压电击后不同时间内,影像组家兔膝关节肌肉损伤区不同位置在不同b值作用下的表观扩散系数(Apparent Diffusion Coeffecient,ADC)值进行检测。结果高压电击伤后,膝关节软组织呈现完全坏死、部分坏死、软组织水肿等三种状态;电击伤后家兔肢体肿胀、皮下软组织肿胀、皮下积液,肢体软组织信号中弥漫性稍长T2信号范围增加;b值越大,ADC值越低;损伤区的深层、浅层、边缘对应的ADC值逐渐降低;电击伤后48 h,b值取600、800、1000、1200 s/mm^(2)时对应的ADC值均低于b=400 s/mm^(2)时的ADC值(P<0.05)。结论磁共振常规联合多b值DWI序列能够对家兔肢体高压电击伤软组织损伤情况进行有效的诊断。Objective To investigate the diagnostic value of MRI and DWI sequence with multi b value in the diagnosis of high voltage electrical injury of limbs in rabbits.Methods A total of 30 clean rabbits were randomly divided into case group(n=16)and imaging group(n=14).One rabbit in case group was killed at 2,24,48 and 72 h after high-voltage shock,and pathological sections and HE staining were performed.The apparent diffusion coeffecient(ADC)values of different sections of knee joint muscle injury in different time after high-voltage electric shock was detected by MRI scan combined with Multi-b value DWI and enhanced scaning.Results After high-voltage electric injury,the soft tissue of knee joint presented three states:complete necrosis,partial necrosis and soft tissue edema.After electric injury,the limb of rabbit was swelled,as well as the subcutaneous soft tissue.The subcutaneous fluid was accumulated,and the diffuse T2 signal range in the limb soft tissue signal was slightly longer.The higher the b value,the lower the ADC value;ADC value of deep,shallow and edge of the injury area gradually decreased;48 hours after electric injury,the ADC values of 600,800,1000 and 1200 s/mm^(2) were lower than those of b=400 s/mm^(2)(P<0.05).Conclusion MRI combined with multi b-value DWI sequence can effectively diagnose the soft tissue injury of high voltage electrical injury in the limbs of rabbits.
分 类 号:R445.2[医药卫生—影像医学与核医学] R576[医药卫生—诊断学]
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