胃肠镜一元复方过氧乙酸消毒和灭菌效果及经济成本  

Effect of one-yuan compound peracetic acid on disinfection and sterilization of gastrointestinal endoscopes and economic cost

作　　者：金雁[1] 李翠[1] 林晓雪 姜璐 林玲 JIN Yan;LI Cui;LIN Xiao-xue;JIANG Lu;LIN Ling(The Fourth Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang 150001,China)

机构地区：[1]哈尔滨医科大学附属第四医院医用消耗物资管理库,黑龙江哈尔滨150001

出　　处：《中华医院感染学杂志》2021年第22期3504-3507,共4页Chinese Journal of Nosocomiology

基　　金：中国老年医学会医院感染防控研究基金资助项目(GRYJ-QR2018034)。

摘　　要：目的探讨某国产一元复方过氧乙酸消毒剂用于胃肠镜的消毒和灭菌效果及经济成本。方法选取哈尔滨医科大学附属第四医院2019年8月-12月患者使用后的胃肠镜800例次,其中500例次用于消毒实验,300例次用于灭菌实验。用于消毒实验的胃肠镜随机分为两组,分别采用一元复方过氧乙酸消毒剂和邻苯二甲醛消毒液消毒。用于灭菌实验的胃肠镜随机分为三组,分别采取一元复方过氧乙酸消毒剂浸泡、环氧乙烷低温灭菌和过氧化氢低温等离子灭菌的方法进行灭菌。消毒和灭菌合格标准遵照行业标准WS507-2016《软式内镜清洗消毒技术规范》判定。结果消毒效果比较:一元复方过氧乙酸消毒剂和邻苯二甲醛消毒液消毒内镜的合格率分别为96.80%和96.00%,均未检测出致病性微生物,比较无统计学差异。一元复方过氧乙酸消毒剂单条消毒成本低于邻苯二甲醛消毒液。灭菌效果比较:一元复方过氧乙酸消毒剂、环氧乙烷低温灭菌、过氧化氢低温等离子灭菌合格率分别为98.00%、99.00%和100.00%,均未检测出致病性微生物,比较无统计学差异。一元复方过氧乙酸消毒剂灭菌时间最短,单条内镜灭菌成本最低。结论一元复方过氧乙酸消毒剂具有良好的消毒和灭菌功能且经济成本较低,其灭菌时间较短,非常适用于内镜灭菌周期长,数量周转不足的医院。OBJECTIVE To explore the effect of a domestic one-yuan compound peracetic acid disinfectant on disinfection and sterilization of gastrointestinal endoscopes and observe the economic costs. METHODS The gastrointestinal endoscopes that were used for 800 case times by the patients in the Fourth Affiliated Hospital of Harbin Medical University from Aug 2019 to Dec 2019 were enrolled in the study, 500 cases times of which were used for disinfection experiment, and 300 case times were used for sterilization experiment. The gastrointestinal endoscopes that were used for disinfection experiment were randomly divided into two groups and were respectively disinfected with one-yuan compound peracetic acid disinfectant and O-phthalaldehyde disinfectant. The gastrointestinal endoscopes that were used for sterilization experiment were randomly divided into three groups and were respectively treated with one-yuan compound peracetic acid disinfectant soaking, low temperature sterilization with ethylene oxide and hydrogen peroxide low temperature plasma sterilization. The effects of disinfection and sterilization were determined on basis of industry standard WS507-2016 "Technical Specification for Cleaning and Disinfection of Flexible Endoscopes". RESULTS As compared with the effect of disinfection, the qualified rates of one-yuan compound peracetic acid disinfectant and O-phthalaldehyde disinfectant were respectively 96.80% and 96.00%, without pathogenic microorganisms being detected, and there was no significant difference. The cost of single piece of disinfection of the one-yuan compound peracetic acid disinfectant was less than that of the O-phthalaldehyde disinfectant. As compared with the effect of sterilization, the qualified rates of the one-yuan compound peracetic acid disinfectant, the low temperature sterilization with ethylene oxide and the hydrogen peroxide low temperature plasma sterilization were respectively 98.00%, 99.00% and 100.00%, without pathogenic microorganism being detected, and there was no significant d

关 键 词：胃肠镜 复方过氧乙酸 消毒效果 灭菌效果 经济成本 

分 类 号：R472.1[医药卫生—护理学]