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作 者:杨倩 雷一腾 马贝贝 朱涛[2] 蒋中英 YANG Qian;LEI Yi-Teng;MA Bei-Bei;ZHU Tao;JIANG Zhong-Ying(Key Laboratory of Micro-nano Electric Sensing Technology and Bionic Devices,College of Electronic and Information Engineering,Yili Normal University,Yining 835000,China;National Laboratory of Solid State Microstructures,School of Physics,Nanjing University,Nanjing 210093,China;Xinjiang Laboratory of Phase Transitions and Microstructures in Condensed Matter Physics,College of Physical Science and Technology,Yili Normal University,Yining 835000,China)
机构地区:[1]伊犁师范大学电子与信息工程学院微纳电传感技术与仿生器械重点实验室,伊宁835000 [2]南京大学物理学院固体微结构物理国家重点实验室,南京210093 [3]伊犁师范大学物理科学与技术学院新疆凝聚态相变与微结构实验室,伊宁835000
出 处:《原子与分子物理学报》2022年第1期63-68,共6页Journal of Atomic and Molecular Physics
基 金:新疆自治区自然科学基金(2020D01C266);新疆自治区研究生科研项目(XJ2020G302);国家自然科学基金(11904167,11774147)。
摘 要:纳米颗粒在生物膜表面的吸附对其生物医学应用至关重要.在本研究中,采用正置与倒置石英电子微天平及耗散系数测量实验,表征了不同溶液高度的支撑膜表面金纳米棒的吸附动力学.发现金棒在重力场下产生溶液浓度不均性.长宽比增大能够提高金棒的流体力学尺寸,延缓金棒的不均再分布过程,从而维持不同溶液高度生物膜表面吸附量的一致.同时,由于浓度不均程度差异,短棒、中棒、长棒在不同溶液高度的吸附量排序关系也是变化的.在溶液底层短棒的吸附量最大,在溶液顶层中棒的吸附量最大.研究深化考察了调控纳米颗粒在生物膜表面吸附的物理因素,为纳米材料的医学应用提供了参考.The adsorption of nanoparticles onbiomembranes is critical for biomedical applications.In this research,we studied the adsorption kinetics of gold nanorods on supported lipid membranes at the diverse heights of medium using the upright and inverted quartz crystal microbalance with dissipation experiments.The nanorod’s concentration becomes heterogeneous under the gravity field.A growth of aspect ratio increases the hydrodynamic size of gold nanorods,delays the redistribution process for heterogeneity,and helps to maintain an identical adsorption amount at diverse heights of the medium.And as the result of the different concentration heterogeneities for the long,middle,and short nanorods,the increasing order of adsorption amount also changes with the height of the medium.The short nanorods adsorb highest at the bottom,while the middle nanorods adsorb highest at the top.This research investigated the physical factors regulating the adsorption of nanoparticles on biomembranes,and can provide a reference for the medical application of nanomaterials.
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