机构地区:[1]海南医学院第二附属医院,海南海口570311 [2]广西壮族自治区北海市人民医院,广西北海536006 [3]四川省泸州市妇幼保健院,四川泸州646000
出 处:《康复学报》2021年第6期501-507,共7页Rehabilitation Medicine
基 金:海南省自然科学基金项目(820MS145);海南省医药卫生科研项目(1801036030A2001)。
摘 要:目的:观察干扰电刺激八髎穴、大肠俞穴联合口服莫沙必利治疗糖尿病便秘患者的临床疗效。方法:选择2018年1月—2019年12月在海南医学院第二附属医院住院治疗的糖尿病便秘患者40例,采用随机数字表法分为对照组和观察组,每组20例。对照组在生活方式干预基础上给予口服莫沙必利片治疗,5 mg/次,3次/d,持续治疗2周。观察组在对照组基础上给予干扰电(ICT)穴位刺激,穴位选择双侧“八髎穴”和“大肠俞穴”,频率(4000±100)Hz,强度以患者能耐受为度,20 min/次,1次/d,持续治疗2周。分别于治疗前后采用多功能生物刺激反馈仪测量盆底肌表面肌电;采用Laycock评分体系评估盆底肌力;采用健康调查简表(SF-36)评估患者生活质量;采用便秘症状积分评定表评估其便秘症状;比较2组临床疗效。结果:2组治疗前盆底肌表面肌电、盆底肌力、生活质量评分比较,差异无统计学意义(P>0.05)。①盆底肌表面肌电值:与治疗前比较,2组治疗后前基线平静期肌电、后基线平静期肌电降低,快肌收缩期肌电、综合肌收缩期肌电及慢肌收缩期肌电均明显升高(P<0.05);与对照组比较,观察组治疗后前基线平静期肌电、后基线平静期肌电明显降低,快肌收缩期肌电、综合肌收缩期肌电及慢肌收缩期肌电明显升高,差异有统计学意义(P<0.05)。②盆底肌力:与治疗前比较,2组治疗后盆底肌力明显升高(P<0.05);与对照组比较,观察组治疗后盆底肌力明显升高,差异有统计学意义(P<0.05)。③临床疗效:与治疗前比较,2组排便间隔时间、粪便性状、排便困难/费力、排便不尽感、肛门/直肠阻塞感等便秘症状积分均明显降低(P<0.05);与对照组比较,观察组便秘症状积分明显降低(P<0.05)。观察组临床疗效优于对照组,差异有统计学意义(P<0.05)。④SF-36评分:与治疗前比较,2组治疗后SF-36评分均明显升高(P<0.05);与对照组比较,观察组Objective: To observe the clinical effect of interference electric stimulation at Baliao and Dachangshu acupoints combined with mosapride on constipation patients with diabetes. Methods:A total of 40 constipation patients with diabetes in the outpatient department of the Second Affiliated Hospital of Hainan Medical College from January 2018 to December 2019 were randomly assigned to the control group and the observation group, with 20 cases in each group. The control group was treated with oral mosapride plus lifestyle intervention, and Mosapride was given orally five mg a time, three times a day, continuous treatment for two weeks. The observation group received interference electric stimulation at Baliao and Dachangshu acupoints on the basis of oral mosapride and lifestyle intervention. The frequency was(4 000±100) Hz, and the intensity was subject to the patient’s tolerance, 20 minutes each time, once a day, continuous treatment for two weeks. Before and after treatment, the surface electromyography(EMG) of pelvic floor muscle was measured by multifunctional biological stimulation feedback instrument, the pelvic floor muscle strength was evaluated by Laycock score system, the quality of life of patients was evaluated by the MOS item short from health survey(SF-36), the constipation symptoms were evaluated by constipation symptom score scale, and the clinical effects of two groups were compared. Results:There was no significant difference in the scores of pelvic floor surface EMG, pelvic floor muscle strength and quality of life between the two groups before treatment(P>0.05).(1) Pelvic floor electromyography: compared with that before treatment, the Pre baseline resting EMG and Post baseline resting EMG were decreased significantly(P<0.05), and the fast muscle systolic EMG, systolic EMG of synthetic muscle and slow muscle systolic EMG of two groups after the treatment were increased significantly(P<0.05);compared with the control group, the Pre baseline resting EMG and Post baseline resting EMG in the obser
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