急性肾损伤后肾功能恢复研究进展  

Research progress on the recovery of renal function after acute renal injury

作　　者：杨晓玲 袁琪茜 张官文 李群 陈宇[1] 董晨明[1] Yang Xiao-ling;Yuan Qi-xi;Zhang Guan-wen;Li Qun;Chen Yu;Dong Chen-ming(Department of Critical Care Medicine,Lanzhou University Second Hospital,Laruhou 730030,China)

机构地区：[1]兰州大学第二医院重症医学科,甘肃兰州730030

出　　处：《中国急救医学》2021年第11期998-1003,共6页Chinese Journal of Critical Care Medicine

基　　金：2019年度省级重点人才项目和陇原青年创新创业人才(团队)项目(2019-39-4)。

摘　　要：随着对急性肾损伤(acute kidney injury,AKI)的不断深入研究,人们不再局限于AKI患者的短期预后,越来越多的研究着重于探索AKI后肾功能恢复对患者的长期影响,肾功能恢复对AKI患者的预后已变得越来越重要。然而目前对AKI后肾功能恢复的认识仍然有限,本文就这一主题的相关文献进行综述,旨在帮助临床医生了解AKI发生后肾功能恢复的定义、流行病学特征、病理生理机制、影响AKI后肾脏不恢复的危险因素以及监测肾功能恢复的预测指标和促进肾功能恢复的干预措施。With the continuous in-depth research on acute kidney injury(AKI),the researchers are no longer limited to the short-term prognosis of AKI.More and more clinical studies focus on exploring the long-term impact of renal function recovery after AKI on the patients.Renal function recovery is important for the prognosis of AKI patients increasingly.However,the current researchers’understanding of renal function recovery after AKI is still limited.In this article,the relevant literatures in this field are reviewed to help clinicians understand the definition,epidemiological characteristics and pathophysiological mechanism of kidney function recovery after AKI,as well as the risk factors affecting renal non-recovery after AKI,predictive index of renal function recovery and intervention measures to promote the recovery of renal function.

关 键 词：急性肾损伤(AKI) 肾功能恢复 肌酐 生物标志物 随访 

分 类 号：R692[医药卫生—泌尿科学]