超声造影在移植肾实质性并发症中的诊断价值  

The Value of CEUS in Diagnosing the Complications Related to Substantive Cause After Kidney Transplantation

作　　者：万晓静 董凤林[1] 范晴敏 杨雅静 严俊辰 朱利霞[1] Wan Xiaojing;Dong Fenglin;Fan Qingmin;Yang Yajing;Yan Junchen;Zhu Lixia(Department of Ultrasound,the First Affiliated Hospital of Suzhou University,Suzhou,Jiangsu 215006,China)

机构地区：[1]苏州大学附属第一医院超声科,江苏省苏州市215006

出　　处：《中国超声医学杂志》2021年第12期1381-1384,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：目的探讨常规超声、超声造影在移植肾实质性并发症中的诊断价值。方法回顾性分析移植肾活检病理阳性患者和移植肾功能正常者,所有患者均同时行常规超声、超声造影检查。分析移植肾相关参数在两组间是否有统计学差异。结果移植肾病理阳性组82例(其中急慢性排斥反应组26例,肾小球硬化组21例),功能正常组12例。与功能正常组相比,病理阳性组的移植肾主动脉RI明显升高(P=0.026),叶间动脉PSV明显减低(P=0.019);TIC参数中,病理阳性组的皮、髓质AUC明显减小(P=0.001,P=0.000 1),髓质TTP、ATTP明显延长(P=0.023,P=0.002),上升斜率明显减小(P=0.004)。以上各参数,在急慢性排斥反应组、肾小球硬化组和功能正常组之间均具有统计学意义(P<0.05)。结论对于移植肾实质性并发症的诊断,常规超声及超声造影具有一定的应用价值。Objective To investigate the value of various quantitative parameters of conventional ultrasound(US),contrast-enhanced ultrasound(CEUS)of renal allograft in diagnosing the complications related to substantive cause after kidney transplantation.Methods Patients with pathologically positive renal graft biopsy and normal renal graft function were retrospectively analyzed.All patients received conventional ultrasound and CEUS at the same time.To analyze whether there were‘statistical differences between the two groups in the parameters related to renal trans-plantation.Results 82 pathological positive biopsy patients,and 12 stable allograft function patients included.C.om-pared with the stable allograft function group,RI of renal allograft aorta was significantly higher in the puncture path-ologically positive group(P=0.026).PSV of renal allograft interlobular artery was significantly lower(P=0.019).The parameters of CEUS:AUC of the cortex in the positive puncture pathology group was significantly reduced(P=0.001);TTP,ATTP of the medulla were significantly prolonged lower(P=0.023,P=0.002).the ascending slope was significantly reduced(P=0.004).and the AUC was significantly reduced(P=0.0001).Conclusions US and CEUS examination have certain application value to provide some new evidence for the early diagnosis of complications related to substantive causes after kidney transplantation.

关 键 词：移植肾 实质性并发症 活检病理 超声造影 

分 类 号：R699.2[医药卫生—泌尿科学] R445.1[医药卫生—外科学]