肥厚型心肌病患者碎裂QRS波与心血管事件风险相关性的研究进展  

Research advances in relationship between fragmented QRS complex and risk of cardiovascular events in patients with hypertrophic cardiomyopathy

作　　者：李京秀 章富君 高敏[1] 仇鑫 李学奇[3] 王静[1] 王延林 狄欣欣 王慕秋 丁蓓蓓 LI Jingxiu;ZHANG Fujun;GAO Min;QIU Xin;LI Xueqi;WANG Jing;WANG Yanlin;DI Xinxin;WANG Muqiu;DING Beibei(Department of Electrocardiogram,the First Affiliated Hospital of University of Sciences and Technology of China,Hefei Anhui 230001;Department of Electrocardiogram,the Second People’s Hospital of Chizhou,Chizhou Anhui 247000;Department of Cardiology,the Fourth Affiliated Hospital of Harbin Medical University,Harbin Heilongjiang 150001,China)

机构地区：[1]中国科学技术大学附属第一医院心电科,安徽合肥230001 [2]池州市第二人民医院心电科,安徽池州247000 [3]哈尔滨医科大学附属第四医院心血管内科,黑龙江哈尔滨150001

出　　处：《实用心电学杂志》2021年第6期424-427,共4页Journal of Practical Electrocardiology

基　　金：安徽省自然科学基金资助项目(1708085MH227)。

摘　　要：肥厚型心肌病(hypertrophic cardiomyopathy,HCM)是心血管内科临床中常见的疾病之一,循证医学证据表明HCM亦是导致心脏性猝死的常见原因之一,因此,预测HCM患者的恶性心血管事件风险尤为重要。作为心电学无创指标之一的碎裂QRS波(fragmented QRS complex,fQRS),其产生机制与心肌瘢痕所引起的传导延迟密切相关,因具有测量方便、快捷等优点而受到业界的重视。本文整理分析了2013—2020年HCM伴fQRS患者相关的国内外临床研究及荟萃分析资料,结果提示fQRS可作为HCM患者室性心律失常、心脏性猝死风险等高危心血管事件的预警靶标,且对评估随访患者远期预后有重要的临床意义。Hypertrophic cardiomyopathy(HCM)is one of common diseases in the department of cardiovascular medicine.Evidences of evidence-based medicine indicate that HCM also contributes to sudden cardiac death.Therefore,it is especially vital to evaluate the risk of malignant cardiovascular events among HCM patients.As one of non-invasive ECG indicators,fragmented QRS complex(fQRS)is strongly suggestive of conduction delay resulted from myocardial scars.It attracts attention of clinicians for its advantages of being convenient and rapid to measure.This paper sorts and analyzes references of clinical studies and meta-analysis at home and abroad related to HCM patients complicated by fQRS published from 2013 to 2020.The results suggest that fQRS could serve as an early-warning indicator of high-risky cardiovascular events including ventricular arrhythmia and sudden cardiac death in HCM patients,and it proves to be clinically significant for evaluating the long-term prognosis of followed up patients.

关 键 词：肥厚型心肌病 碎裂QRS波 心电图 心血管事件 

分 类 号：R542.2[医药卫生—心血管疾病] R540.41[医药卫生—内科学]