2010—2019年成都市梅毒流行特征及变化趋势分析  

Analysis on epidemic characteristics and trend of syphilis in Chengdu City from 2010-2019

作　　者：何世娇 代珍[1] 徐菁佩 范双凤[1] 何勤英[1] HE Shi-jiao;DAI Zhen;XU Jing-pei;FAN Shuang-feng;HE Qin-ying(STD and AIDS Prevention and Control Department,Center for Disease Control and Prevention of Chengdu,Chengdu Sichuan,610041,China)

机构地区：[1]成都市疾病预防控制中心性病与艾滋病防制科,四川成都610041

出　　处：《职业与健康》2021年第21期2964-2967,共4页Occupation and Health

摘　　要：目的了解2010—2019年成都市梅毒流行特征及变化趋势,为制定有效的梅毒防控策略提供参考依据。方法采用描述流行病学方法对2010—2019年成都市梅毒疫情数据进行分析。结果 2010—2019年成都市累计报告梅毒病例49 905例,年平均发病率为33.86/10万,报告发病率从41.66/10万上升至46.66/10万,年均增长1.27%。Ⅰ期和Ⅱ期梅毒(早期梅毒)发病率从2010年的18.49/10万下降至2019年的6.38/10万,年均降低11.15%。在梅毒病例构成中,以隐性梅毒为主,占71.80%,其构成比从2010年的51.98%上升至2019年的85.01%。女性发病率(35.49/10万)高于男性(32.26/10万),2010—2019年间发病率分别增长1.26%和1.28%。20~<30岁年龄组人群发病率最高,为53.00/10万,其次为≥60岁年龄组人群(45.07/10万),2010—2019年间20~<30岁年龄组发病率呈下降趋势,年均降低6.92%,50~<60岁和≥60岁年龄组发病率则呈明显上升趋势,年均增长速度分别为10.34%和4.29%。结论 2010—2019年成都市早期梅毒发病呈下降趋势,但隐性梅毒报病持续增加,中老年人群梅毒疫情不断上升,防治形势依然严峻,应结合疫情特点制定更有针对性的干预措施,控制梅毒的流行。Objective To understand the epidemic characteristics and trend of syphilis in Chengdu City from 2010-2019,provide evidence for developing effective prevention and control strategies of syphilis. Methods Descriptive epidemiology methods were used to analyze the syphilis epidemic data in Chengdu City from 2010-2019. Results From 2010 to 2019,a total of 49 905 syphilis cases were reported in Chengdu City,with an average annual incidence of 33.86/lakh,and the incidence increased from41.66/lakh to 46.66/lakh,with an average annual growth rate of 1.27%. The incidence of stage Ⅰand Ⅱ syphilis(early syphilis)decreased from 18.49/lakh in 2010 to 6.38/lakh in 2019,with an average annual reduction rate of 11.15%. In the case composition of syphilis,latent syphilis accounted for 71.80%,and its proportion increased from 51.98% in 2010 to 85.01% in2019. The incidence of syphilis was higher in females(35.49/lakh) than in males(32.26/lakh),with an average annual growth rate of 1.26% and 1.28% respectively from 2010 to 2019. The highest incidence was 53.00/lakh in the age group of 20-<30 years old,followed by the age group of ≥60 years old(45.07/lakh). The incidence in the age group of 20-<30 years old decreased with an average annual reduction rate of 6.92%,while increased in the age groups of 50-<60 and ≥60 years old with an average annual growth rate of 10.34% and 4.29% respectively from 2010 to 2019. Conclusion From 2010 to 2019,the incidence of early syphilis shows a downward trend in Chengdu City,however,the latent syphilis cases continue to increase and the incidence of syphilis among middle-aged and elderly people is on the rise. Therefore,the situation of syphilis prevention and control is still grim. More targeted interventions should be developed based on the characteristics of the epidemic to control the prevalence of syphilis.

关 键 词：梅毒 发病率 流行病学特征 变化趋势 

分 类 号：R181.8[医药卫生—流行病学]