糖尿病对冠状病毒肺炎患者不良结局的影响及损伤机制的研究进展  

Advance on clinical characteristics and injury mechanism of diabetic patients with coronavirus pneumonia

作　　者：刘正茹 董卫国[1] LIU Zhengru;DONG Weiguo(Dept.of Gastroenterology,Renmin Hospital of Wuhan University,Wuhan 430060,Hubei,China)

机构地区：[1]武汉大学人民医院消化内科,湖北武汉430060

出　　处：《武汉大学学报（医学版）》2021年第6期888-894,共7页Medical Journal of Wuhan University

基　　金：国家自然科学基金资助项目(编号:81870392)。

摘　　要：目前已知的可感染人类的冠状病毒有7类,其中,严重急性呼吸窘迫综合征冠状病毒(SARS-CoV)、中东呼吸综合征冠状病毒(MERS-CoV)和新型冠状病毒(SARS-CoV-2)是近20年来对人类健康影响最大的三种冠状病毒。免疫力低下的糖尿病患者感染这三类冠状病毒可能出现不良结局且存在不同的损伤机制。本文就糖尿病对冠状病毒肺炎患者不良结局的影响及损伤机制的研究进展加以综述,以引起临床医生对糖尿病患者合并冠状病毒感染的重视,从而为新型冠状病毒肺炎的治疗提供一定的帮助。Currently,there are seven types of coronaviruses that can infect humans.Among them,severe acute respiratory syndrome coronavirus(SARS-CoV),middle east respiratory syndrome coronavirus(MERS-CoV) and severe acute respiratory syndrome coronavirus-2(SARS-CoV-2) are three types of coronavirus which have the greatest impact on human health in the past 20 years.Diabetic patients with hypoimmunity may have adverse outcomes and different injury mechanisms when infected with coronaviruses.This review is about the advance on clinical characteristics and injury mechanism of diabetic patients with SARS-CoV,MERS-CoV,or SARS-CoV-2.The purpose of writting this review is to arouse the attention of clinicians to diabetic patients with coronavirus infection and provide help for clinicians in the treatment of coronavirus disease 2019.

关 键 词：糖尿病 冠状病毒 严重急性呼吸窘迫综合征冠状病毒(SARS-CoV) 中东呼吸综合征冠状病毒(MERS-CoV) 新型冠状病毒(SARS-CoV-2) 

分 类 号：R587.1[医药卫生—内分泌] R512.9[医药卫生—内科学]