2017-2019年凉山州梅毒感染产妇妊娠梅毒治疗及影响因素分析  

Analysis on the treatment of syphilitic pregnant women and associated factors in Liangshan Prefecture,Sichuan Province,2017-2019

作　　者：马永娟 乔亚萍[2] 吴君梅 林霞 樊鹤莹 彭竞 高建梅 MA Yongjuan;QIAO Yaping;WU Junmei;LIN Xia;FAN Heying;PENG Jing;GAO Jianmei(Liangshan Yi Autonomous Prefecture Center for Maternal and Child Care and Family Planning Service,Xichang 615000,Sichuan,China;The National Center for Women and Children's Health,China CDC,Beijing 100081)

机构地区：[1]凉山州妇幼保健计划生育服务中心,四川西昌615000 [2]中国疾病预防控制中心妇幼保健中心,北京100081

出　　处：《中国艾滋病性病》2021年第11期1287-1291,共5页Chinese Journal of Aids & STD

摘　　要：目的分析2017-2019年四川省凉山州梅毒感染产妇妊娠期抗梅毒治疗及相关影响因素。方法利用全国预防梅毒母婴传播管理信息系统数据,回顾性描述2017-2019年已分娩梅毒产妇妊娠期梅毒治疗特征及其随时间变化趋势,采用χ2检验和Logistic回归模型分析妊娠期梅毒治疗和规范治疗的影响因素。结果本研究共纳入1019例梅毒感染产妇,其中914人(89.7%)在妊娠期接受过治疗,141人(13.8%)接受了规范治疗。2017-2019年,梅毒感染产妇接受规范治疗比例由10.2%(31/305)增加至19.2%(76/396)(χ_(趋势)^(2)=15.61,P<0.001)。多因素分析显示,梅毒感染孕产妇的初次产检孕周、妊娠梅毒诊断时期与治疗率、规范治疗均存在关联。丈夫/性伴目前梅毒感染状况与孕产妇接受规范治疗存在关联。结论凉山州梅毒感染孕产妇治疗率较高,但规范治疗率处于较低水平。促进孕妇早发现、早诊断是落实预防梅毒母婴传播工作的关键。Objective To analyze the treatment status of syphilitic women and associated factors in Liangshan Prefecture,Sichuan province,China,2017-2019.Methods Data from the Management Information System of China’s Prevention of Syphilis Program were used to describe the characteristics of anti-syphilis treatment in pregnant women and their trends over time.The chi-square test and logistic regression model were applied to analyze the associated factors with the anti-syphilis treatment and standardized treatment.Results 1019 syphilis-infected pregnant women were enrolled in the study.Among those,914(89.7%)received treatment,including 141(13.8%)with standard treatment.The proportion of standard treatment increased from 10.2%(31/305)and to 19.2%(76/396)(χ_(trend)^(2)=15.61,P<0.001),respectively during 2017-2019.The treatment proportion and the standard treatment rate were associated with The gestational week of the initial examination for syphilitic pregnant women and the diagnosis time of this syphilis.The standard treatment rate was associated with the current status of syphilis infection of the husband or sexual partner.In Conclusion The treatment rate of syphilitic pregnant women was high while the standard treatment rate was low in Liangshan during 2017-2019.Promoting early detection and early diagnosis of pregnant women is the key to preventing mother-to-child transmission of syphilis.

关 键 词：梅毒感染孕产妇 梅毒治疗 影响因素 

分 类 号：R759.1[医药卫生—皮肤病学与性病学]