妊娠期恶心呕吐防治的证据总结  

Evidence summary of prevention and treatment of nausea and vomiting during pregnancy

作　　者：刘益君 翟巾帼[1] 庄云婷 陈世艺 郑一非 张莉[2] Liu Yijun;Zhai Jinguo;Zhuang Yunting;Chen Shiyi;Zheng Yifei;Zhang Li(School of Nursing,Southern Medical University,Guangzhou 510515,China;Department of Obstetrics and Gynecology,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China)

机构地区：[1]南方医科大学护理学院,广州510515 [2]南方医科大学南方医院妇产科,广州510515

出　　处：《中华现代护理杂志》2021年第33期4546-4550,共5页Chinese Journal of Modern Nursing

基　　金：南方医科大学2020年度校级大学生创新创业训练计划项目(X202012121268);国家教育部人文社会科学研究规划基金项目(18YJC880117)。

摘　　要：目的筛选、获取国内外有关妊娠期恶心呕吐防治的证据,并对证据进行质量评价和汇总。方法计算机检索JBI、UpToDate、the Cochrane Library、PubMed、BMJ、中国生物医学文献数据库、CNKI、万方数据库、医脉通、维普。检索时限均为2011年1月1日—2021年1月1日。由4名研究员独立筛选文献,对符合质量标准的文献进行证据提取和总结。结果共纳入16篇文献,包括4篇指南、1篇证据总结、8篇系统评价、2篇Meta分析及1篇专家共识。通过对妊娠期恶心呕吐防治的循证证据的筛选与获取,最终从评估及诊断、分类分级、风险因素、基本处理原则、预防、非药物治疗、药物治疗等7个方面总结了32条最佳证据。结论妊娠期恶心呕吐的防治应先对患者进行评估,判断患者的症状及严重程度,分析风险因素,从而对患者进行认知、心理及行为干预,并进行非药物治疗或药物治疗。Objective To screen,obtain domestic and foreign evidence on the prevention and treatment of nausea and vomiting during pregnancy,and evaluate and summarize the quality of the evidence.Methods We searched the Joanna Briggs Institute(JBI),UpToDate,the Cochrane Library,PubMed,British Medical Journal(BMJ),Chinese Biomedical Literature Database,China National Knowledge Infrastructure(CNKI),WanFang Data,Yimaitong,VIP by computer.The search time limit was from January 1,2011 to January 1,2021.Four researchers independently screened the articles,and extracted and summarized the evidence that met the quality standards.Results A total of 16 articles were included,including 4 guidelines,1 evidence summary,8 systematic reviews,2 Meta-analysis and 1 expert consensus.Through the screening and acquisition of evidence for the prevention and treatment of nausea and vomiting during pregnancy,the 32 best evidences were finally summarized from 7 aspects including assessment and diagnosis,classification and grading,risk factors,basic management principles,prevention,non-drug treatment,and drug treatment.Conclusions The prevention and treatment of nausea and vomiting during pregnancy should first evaluate the patient,determine the patient's symptoms and severity,analyze the risk factors,and conduct cognitive,psychological,and behavioral interventions for the patient,as well as non-pharmacological or drug treatment.

关 键 词：妊娠 恶心 呕吐 预防 治疗 证据总结 

分 类 号：R473.71[医药卫生—护理学]