中医体质类型与2型糖尿病相关性的系统评价  

Systematic Review on the Relationship between TCM Constitution Types and Type 2 Diabetes Mellitus

作　　者：李红[1] 谭年花 陈斌[1] 张月娟[1] LI Hong;TAN Nian-hua;CHEN Bin;ZHANG Yue-juan(The First Hospital of Hunan University of Chinese Medicine,Changsha Hunan 410007,China;Hunan University of Chinese Medicine,Changsha Hunan 410208,China)

机构地区：[1]湖南中医药大学第一附属医院,湖南长沙410007 [2]湖南中医药大学,湖南长沙410208

出　　处：《中医药导报》2021年第11期211-216,共6页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：湖南省高层次卫生人才“225”工程学科带头人培养项目(湘卫函[2019]196号)。

摘　　要：目的:系统评价中医体质类型与2型糖尿病相关性,探究2型糖尿病患者中医体质的分布规律,为其临床防治提供循证医学证据。方法:以"2型糖尿病""中医体质"为主题检索词,检索中国知网(CNKI)、中国生物医学文献服务系统(CBM)、万方(Wanfang)及维普(VIP)数据库自建库至2021年5月关于2型糖尿病与中医体质相关性研究的文献,依次进行文献筛选、质量评价,提取各体质类型在2型糖尿病患者中的分布数据。采用Review Manager 5.3软件对纳入的文献进行Meta分析。结果:最终纳入17篇研究文献,2型糖尿病患者8405例,2型糖尿病患者各中医体质类型所占比例依次为平和质26.72%[RD=0.24,95%CI(0.15,0.33)]、阴虚质15.62%[RD=0.18,95%CI(0.13,0.22)]、痰湿质15.57%[RD=0.16,95%CI(0.11,0.21)]、气虚质14.37%[RD=0.15,95%CI(0.12,0.19)]、阳虚质10.84%[RD=0.11,95%CI(0.08,0.14)]、湿热质6.17%[RD=0.07,95%CI(0.05,0.09)]、血瘀质5.81%[RD=0.06,95%CI(0.04,0.08)]、气郁质3.53%[RD=0.04,95%CI(0.03,0.05)]、特禀质1.36%[RD=0.01,95%CI(0.01,0.02)],差异均有统计学意义(P<0.01)。男性最常见偏颇体质为痰湿质18.24%[RD=0.17,95%CI(0.11,0.24)],女性最常见偏颇体质为阳虚质16.62%[RD=0.17,95%CI(0.13,0.21)]。结论:2型糖尿病患者最常见的中医体质类型为平和质、阴虚质、痰湿质、气虚质及阳虚质,男性、女性最常见的偏颇体质分别为痰湿质、阳虚质。Objective:To systematically evaluate the correlation between TCM Constitution types and type 2 diabetes mellitus,explore the distribution law of TCM Constitution of Type 2 diabetes mellitus,and provide some evidence-based medicine for their clinical prevention and treatment.Methods:Taking"Type 2 diabetes mellitus"and"TCM Constitution"as the keywords,we searched the literatures on the correlation between Type2 diabetes mellitus and TCM Constitution in CNKI,CBM,Wanfang and VIP databases from the establishment of the database to May 2021.We conducted literature screening and quality evaluation in turn,and extracted the distribution data of each constitution type in type 2 diabetes mellitus.Review Manager 5.3 software was used for meta-analysis of the included literatures.Results:A total of 17 studies were included,including 8405 patients with type 2 diabetes.And the results showed that the ratio of TCM Constitution Types in Type 2 diabetes mellitus were gentleness constitution accounting for 26.72%[RD=0.24,95%CI(0.15,0.33)],Yin-deficiency constitution accounting for 15.62%[RD=0.18,95%CI(0.13,0.22)],phlegm-dampness constitution accounting for15.57%[RD=0.16,95%CI(0.11,0.21)],Qi-deficiency constitution accounting for 14.37%[RD=0.15,95%CI(0.12,0.19)],Yang-defi ciency constitution accounting for 10.84%[RD=0.11,95%CI(0.08,0.14)],damp-heat constitution accounting for 6.17%[RD=0.07,95%CI(0.05,0.09)],blood-stagnation constitution accounting for 5.81%[RD=0.06,95%CI(0.04,0.08)],Qi-stagnation constitution accounting for 3.53%[RD=0.04,95%CI(0.03,0.05)],and special-constitutio accounting for 1.36%[RD=0.01,95%CI(0.01,0.02)]respectively.The difference was statistically significant(P<0.01).The most common biased constitution of male was phlegm-dampness constitution accounting for18.24%[RD=0.17,95%CI(0.11,0.24)]and the most common biased constitution of female was Yang-deficiency constitution accounting for 16.62%[RD=0.17,95%CI(0.13,0.21)].Conclusion:The most common TCM constitution types of type 2 diabetes mellitus are gentleness co

关 键 词：2型糖尿病 中医体质 系统评价 META分析 

分 类 号：R255.4[医药卫生—中医内科学]