A Teosinte-derived Allele of a MYB Transcription Repressor Confers Multiple Disease Resistance in Maize.  

作　　者：Hongze Wang Jiabao Hou Pei Ye Long Hu Junshi Huang Zhikang Dai Bao Zhang Sha Dai Jiamin Que Haoxuan Min Gengshen Chen Yanbo Wang Min Jiang Yan Liang Lin Li Xuecai Zhang Zhibing Lai 

机构地区：[1]National Key Laboratory of Crop Genetic Improvement,Wuhan,China [2]Liaoning Academy of Agricultural Sciences,Shenyang,China [3]International Maize and Wheat Improvement Center(CIMMYT),EI Batan,Texcoco,Mexico

出　　处：《Molecular Plant》2021年第11期1846-1863,共18页分子植物（英文版）

基　　金：This work was supported by the National Key Research and Development Program of China(2016YFD0101002);the National Natural Science Foundation of China(31571676,32072007,and 31761143008);the Ministry of Science and Technology of the People's Republic of China(2015BAD02B01);the Fundamental Research Funds for the Central Universities(2014PY054 and 2662015PY185);the University Student Research Fund(2016090);the Innovation Training Plan of University Student Fund(201510504023);the Higher Education Discipline Innovation Project(B20051).

摘　　要：Natural alleles controlling multiple disease resistances (MDR) are valuable for crop breeding. However, only one MDR gene have been cloned in maize, and molecular mechanisms of MDR are not clear. By map-based cloning, we have cloned a teosinte-derived allele of a resistance gene, Mexicana lesion mimic 1 (ZmMM1), which has a lesion mimic phenotype and confers resistance to northern leaf blight (NLB), gray leaf spot (GLS) and southern corn rust (SCR). Strong MDR conferred by the teosinte allele is linked with the polymorphisms in the 3' untranslated region of the ZmMM1 gene that cause increased accumulation of ZmMM1 protein. ZmMM1 acts as a transcription repressor and negatively regulates transcription of specific target genes including ZmMM1-target gene 3 (ZmMT3), which functions as a negative regulator of plant immunity and associated cell death. The successful isolation of the ZmMM1 resistance gene will help not only in developing broad-spectrum and durable disease resistance but also in understanding the molecular mechanisms underlying MDR.

关 键 词：Multiple disease resistance ZmMM1 lesion mimic MAIZE TEOSINTE 

分 类 号：S513[农业科学—作物学] Q94[生物学—植物学]