糖尿病合并非梭状菌皮肤软组织产气性感染二例临床诊疗分析  

Non-clostridial Gas-forming Infection in Diabetes:Clinical Analysis of Two Cases

作　　者：吴远 吕宏军 姚孝礼 刘娟[1] WU Yuan;LYU Hongjun;YAO Xiaoli;LIU Juan(Department of Endocrinology and Metabolism,the First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,China)

机构地区：[1]西安交通大学第一附属医院内分泌代谢科,陕西省西安市710061

出　　处：《中国全科医学》2022年第3期363-367,共5页Chinese General Practice

基　　金：陕西省创新能力支撑计划(2020KRM171)。

摘　　要：非梭状菌可分解坏死组织中的糖等底物并产生皮下气肿,而非梭状菌皮肤软组织产气性感染常出现在血糖控制不佳的糖尿病患者中。非梭状菌与梭状菌引起产气性感染的鉴别诊断依赖病原学检查结果,但在未取得病原学证据之前早期、联合使用广谱抗生素和及时、有效地清创及必要的手术是救治糖尿病合并非梭状菌皮肤软组织产气性感染患者的关键。本文报道了2例糖尿病合并非梭状菌皮肤软组织产气性感染患者并进行了文献复习,以期提高临床医生对该病的认识。Non-clostridial organism can produce pneumoderma by breaking down sugar and other substrates in necrotic tissues,and non-clostridial gas-forming infection is usually seen in diabetic patients with poor glycemic control.The differential diagnosis between clostridial and non-clostridial gas-forming infection relies on etiological examination results,but the key to successful treatment is timely empiric broad-spectrum antibiotic treatment and emergency surgical debridement in the absence of a definitive etiologic diagnosis.This paper reported two cases of non-clostridial gas-forming infection in diabetes,and reviewed relevant literature,aiming to improve clinicians'understanding of this disease.

关 键 词：糖尿病 2型 感染 产气性感染 梭状菌 诊断 治疗 

分 类 号：R587.1[医药卫生—内分泌] R63[医药卫生—内科学]