叔丁醇钾促进的硒氰酸酯与腙反应合成硒缩醛  

^(t)BuOK-Promoted Reaction of Selenocyanates and Hydrazones for the Synthesis of Selenoacetals

作　　者：叶浩 任婷婷 吴新星 Ye Hao;Ren Tingting;Wu Xinxing(College of Chemistry and Chemical Engineering,Nantong University,Nantong,Jiangsu 226019;Jiangsu Huachuang Testing Technical Service Co.,Ltd.,Nantong,Jiangsu 226019)

机构地区：[1]南通大学化学化工学院,江苏南通226019 [2]江苏华创检测技术服务有限公司,江苏南通226019

出　　处：《有机化学》2021年第11期4338-4346,共9页Chinese Journal of Organic Chemistry

基　　金：南通大学高层次人才科研基金(No.03083031)资助项目.

摘　　要：以硒氰酸酯和腙为起始物,在碱存在条件下实现了一系列硒缩醛类化合物的合成.本方法对硒氰酸(杂)芳酯以及(杂)芳基、烷基等类型的腙都具有良好的底物适应性和优秀的官能团兼容性,同时适合克级反应制备,为硒缩醛类化合物的高效合成提供了一种实用的新策略.A series of selenoacetals were synthesized from selenocyanates and hydrazones under base condition.(Hetero)aryl selenocyanate and(hetero)aryl,alkyl hydrazones can undergo the process successfully,and shows broad substrate scope and excellent functional group tolerance.This protocol is suitable for gram-scale preparation,providing an efficient and practical synthetic strategy toward selenoacetals.

关 键 词：硒氰酸酯 腙 硒缩醛 重排 

分 类 号：O623.541[理学—有机化学]