钌选择性催化烯丙醇无受体脱氢合成α,β-不饱和羰基化合物  

Ruthenium Catalyzed Selective Acceptorless Dehydrogenation of Allylic Alcohols to α,β-Unsaturated Carbonyls

作　　者：刘嘉豪 张世冬 栾自鸿 刘艳 柯卓锋 Liu Jiahao;Zhang Shidong;Luan Zihong;Liu Yan;Ke Zhuofeng(Key Laboratory for Polymeric Composite&Functional Materials of Ministry of Education,School of Materials Science and Engineering,Sun Yat-sen University,Guangzhou 510006;School of Chemical Engineering and Light Industry,Guangdong University of Technology,Guangzhou 510006)

机构地区：[1]中山大学材料科学与工程学院,聚合物复合材料及功能材料教育部重点实验室,广州510006 [2]广东工业大学轻工化工学院,广州510006

出　　处：《有机化学》2021年第11期4361-4369,共9页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(Nos.21973113,21977019);广东省自然科学杰出青年基金(No.2015A030306027)资助项目.

摘　　要：过渡金属催化烯丙醇的选择性脱氢氧化以得到相应的α,β-不饱和羰基化合物在最近广受关注,但是很多方法需要用到化学计量的氧化剂,这会带来大量的废弃副产物,原子经济性不足.本工作开发了一种简单易得的[RuCl2(pcymene)]2催化系统,可用于高效地催化烯丙醇选择性脱氢合成α,β-不饱和羰基化合物,而无需使用额外的氧化剂或H2受体.Transition metal-catalyzed allyllic alcohol selective dehydrogenation to generate the corresponding α,β-unsaturated carbonyl compound has attached great attention.However,most of these methods require stoichiometric quantities of oxidants,which will bring a lot of by-products and lack of atomic economy.Herein,a simple[RuCl_(2)(p-cymene)]_(2) catalyzed system to efficiently catalyze the selective dehydrogenation of allyl alcohol to form α,β-unsaturated carbonyls without the use of additional oxidants or H2 acceptors has been developed.

关 键 词：钌 无受体脱氢 烯丙醇 Α Β-不饱和羰基化合物 

分 类 号：O621.251[理学—有机化学]